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Keywords: UV
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Journal Articles
J Cell Sci (2017) 130 (23): 4028–4037.
Published: 1 December 2017
... activation of the mitotic cyclin-dependent kinase (CDK) Cdc2 after UV irradiation. Furthermore, we demonstrate that translation of the mitotic cyclin Cdc13 is selectively downregulated after UV irradiation, and we propose that this downregulation of Cdc13 contributes to the delayed activation of Cdc2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (6): 1223–1233.
Published: 15 March 2016
... is one of the key factors for TLS pathway choice. So far, it remains unclear how the TLS pathway is elaborately regulated. Here, we report that TLS polymerase REV1 can promote PCNA monoubiquitylation after UV radiation. Further studies revealed that this stimulatory effect is mediated through...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (23): 4380–4394.
Published: 1 December 2015
... modifications and chromatin accessibility to UV exposure remains poorly understood. Here, we report that UV exposure results in a genome-wide reduction in chromatin accessibility, while the distribution of the active regulatory mark H3K27ac undergoes massive reorganization. Genomic loci subjected to epigenetic...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (19): 4358–4368.
Published: 1 October 2013
.... , Sarasin   A. , Fotedar   A. , Fotedar   R. ( 2003 ). UV irradiation triggers ubiquitin-dependent degradation of p21(WAF1) to promote DNA repair.   Cell   114 , 599 – 610 . 10.1016/j.cell.2003.08.001 Cazzalini   O. , Donà   F. , Savio   M. , Tillhon   M. , Maccario   C...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (9): 1923–1930.
Published: 1 May 2013
...Daniël O. Warmerdam; Eva K. Brinkman; Jurgen A. Marteijn; René H. Medema; Roland Kanaar; Veronique A. J. Smits Summary In response to UV light, single-stranded DNA intermediates coated with replication protein A (RPA) are generated, which trigger the ATR-Chk1 checkpoint pathway. Recruitment...
Includes: Supplementary data
Journal Articles
Journal Articles
Journal Articles
J Cell Sci (2005) 118 (3): 589–599.
Published: 1 February 2005
... are subunits of antibodies used in immunoprecipitation. Apoptotic HL-60 cells were loaded for identification of PARP. Data are from one of five experiments with identical results. Although PARP activation has been implicated in carcinogenesis, DNA repair and cell death after exposure to UV...
Journal Articles
J Cell Sci (2002) 115 (4): 793–803.
Published: 15 February 2002
...Morten P. Oksvold; Henrik S. Huitfeldt; Anne Carine Østvold; Ellen Skarpen We have compared the activation and trafficking of epidermal growth factor receptor (EGFR) induced by UV light and EGF. Tyrosine phosphorylation of EGFR was not detected in UV-exposed cells by immunoblotting of whole cell...