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Keywords: Tyrosine phosphatase
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Journal Articles
J Cell Sci (2019) 132 (7): jcs224568.
Published: 3 April 2019
... of co-transmission. Based on screening in Drosophila for increased presynaptic neuropeptides, the receptor protein tyrosine phosphatase (Rptp) Ptp4E was found to post-transcriptionally regulate neuropeptide content in single DCVs at octopamine synapses. This occurs without changing neuropeptide release...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (15): 3269–3279.
Published: 1 August 2014
... downstream effects on cellular processes. Here, we identify an interaction between the T-cell protein tyrosine phosphatase (TC-PTP, officially known as PTPN2) and the carboxyl terminus of connexin43 (Cx43, officially known as GJA1). Two cell lines, normal rat kidney (NRK) cells endogenously expressing Cx43...
Journal Articles
J Cell Sci (2014) 127 (11): 2420–2432.
Published: 1 June 2014
...-cadherin activates tyrosine kinases, such as Src, that control junctional integrity. Protein tyrosine phosphatases (PTPs) also contribute to cadherin-based adhesion and signaling, but little is known about their specific identity or functions at epithelial junctions. Here, we report that the receptor PTP...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (20): 4841–4852.
Published: 15 October 2012
...Dong-Yuan Chen; Meng-Yen Li; Shih-Yun Wu; Yu-Ling Lin; Sung-Po Tsai; Pei-Lun Lai; Yu-Tsen Lin; Jean-Cheng Kuo; Tzu-Ching Meng; Guang-Chao Chen Summary Protein tyrosine phosphatases (PTPs) are a group of tightly regulated enzymes that coordinate with protein tyrosine kinases to control protein...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (6): 837–841.
Published: 15 March 2010
...-induced serine phosphorylation of the PTP3 protein tyrosine phosphatase inhibits its activity towards STATc. We show that two serine residues in PTP3, S448 and S747, are rapidly phosphorylated after osmotic stress. cGMP is a second messenger for hyperosmotic stress response and 8-bromo-cGMP, a membrane...
Journal Articles
J Cell Sci (2004) 117 (4): 609–618.
Published: 1 February 2004
...Stuart Kellie; Graham Craggs; Ian N. Bird; Gareth E. Jones The receptor protein tyrosine phosphatase density-enhanced phosphatase-1 (DEP-1) has been implicated in aberrant cancer cell growth and immune cell function, however, its function within cells has yet to be properly elucidated...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2003) 116 (7): 1279–1289.
Published: 1 April 2003
...Konstantin Adamsky; Katya Arnold; Helena Sabanay; Elior Peles Receptor protein tyrosine phosphatase β (RPTPβ) mediates cell-cell and cell-matrix interactions. By searching for intracellular proteins that interact with the cytoplasmic region of this phosphatase using the two-hybrid method, we...
Journal Articles
J Cell Sci (2002) 115 (22): 4305–4316.
Published: 15 November 2002
...Sarita K. Sastry; Patrick D. Lyons; Michael D. Schaller; Keith Burridge The cytoplasmic protein tyrosine phosphatase, PTP-PEST, associates with the focal adhesion proteins p130cas and paxillin and has recently been implicated in cell migration. In this study, we investigated the mechanism by which...
Journal Articles
J Cell Sci (2001) 114 (11): 2187–2198.
Published: 1 June 2001
..., the involvement of tyrosine phosphatases in this process is unknown. SHP-2 is an SH2 domain-containing tyrosine phosphatase, which positively regulates growth and differentiation. We show that in C2C12 myoblasts, SHP-2 becomes upregulated early on during myogenesis and associates with a 120 kDa tyrosyl...