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Keywords: Tyrosine kinase
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Journal Articles
J Cell Sci (2010) 123 (2): 236–245.
Published: 15 January 2010
...Helena L. Palka-Hamblin; Jessica J. Gierut; Wenjun Bie; Patrick M. Brauer; Yu Zheng; John M. Asara; Angela L. Tyner Disruption of the gene encoding protein tyrosine kinase 6 (PTK6) leads to increased growth, impaired enterocyte differentiation and higher levels of nuclear β-catenin in the mouse...
Journal Articles
J Cell Sci (2007) 120 (17): 3034–3044.
Published: 1 September 2007
...Camille Faure; Jean-Christophe Corvol; Madeleine Toutant; Emmanuel Valjent; Øivind Hvalby; Vidar Jensen; Said El Messari; Jean-Marc Corsi; Gress Kadaré; Jean-Antoine Girault Proline-rich tyrosine kinase 2 (PYK2) is a non-receptor tyrosine kinase expressed in many cell types and enriched in neurons...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (15): 3039–3048.
Published: 1 August 2002
...Aya Takesono; Lisa D. Finkelstein; Pamela L. Schwartzberg The Tec kinases represent the second largest family of mammalian non-receptor tyrosine kinases and are distinguished by the presence of distinct proline-rich regions and pleckstrin homology domains that are required for proper regulation...
Journal Articles
J Cell Sci (2002) 115 (3): 455–465.
Published: 1 February 2002
... function as GPCR signal transducers. They can form complexes with several signaling proteins,including Src family tyrosine kinases and components of the ERK1/2 and JNK3 MAP kinase cascades. By recruiting these kinases to agonist-occupied GPCRs,β-arrestins confer distinct signaling activities upon...
Journal Articles
J Cell Sci (2001) 114 (14): 2553–2560.
Published: 15 July 2001
... pathway may provide a paradigm for understanding how cell adhesion can determine cell cycle progression. © The Company of Biologists Limited 2001 2001 Tyrosine kinase Signal transduction Growth control Cell adhesion Proliferation of mammalian cells is tightly regulated by multiple...
Journal Articles
J Cell Sci (1994) 1994 (Supplement_18): 121–126.
Published: 1 January 1994
...Lewis C. Cantley; Zhou Songyang SUMMARY SH2 domains and SH3 domains, found in a number of protein-tyrosine kinases and substrates of protein-tyrosine kinases, provide specificity in downstream signaling. Both of these domains bind to relatively short linear sequences of peptides to provide specific...
Journal Articles
J Cell Sci (1993) 1993 (Supplement_17): 223–228.
Published: 1 December 1993
..., and NT-5. These neurotrophin factors interact with two classes of receptors, the trk receptor tyrosine kinase family, and the low affinity p75 neurotrophin receptor. To study potential ligand-receptor interactions, recombinant trk fusion proteins have been constructed, and pan- trk polyclonal antisera...