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Keywords: Tyrosine kinase
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Journal Articles
Journal Articles
J Cell Sci (2007) 120 (17): 3034–3044.
Published: 1 September 2007
...Camille Faure; Jean-Christophe Corvol; Madeleine Toutant; Emmanuel Valjent; Øivind Hvalby; Vidar Jensen; Said El Messari; Jean-Marc Corsi; Gress Kadaré; Jean-Antoine Girault Proline-rich tyrosine kinase 2 (PYK2) is a non-receptor tyrosine kinase expressed in many cell types and enriched in neurons...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (15): 3039–3048.
Published: 1 August 2002
...Aya Takesono; Lisa D. Finkelstein; Pamela L. Schwartzberg The Tec kinases represent the second largest family of mammalian non-receptor tyrosine kinases and are distinguished by the presence of distinct proline-rich regions and pleckstrin homology domains that are required for proper regulation...
Journal Articles
J Cell Sci (2002) 115 (3): 455–465.
Published: 1 February 2002
... function as GPCR signal transducers. They can form complexes with several signaling proteins,including Src family tyrosine kinases and components of the ERK1/2 and JNK3 MAP kinase cascades. By recruiting these kinases to agonist-occupied GPCRs,β-arrestins confer distinct signaling activities upon...
Journal Articles
J Cell Sci (2001) 114 (14): 2553–2560.
Published: 15 July 2001
... pathway may provide a paradigm for understanding how cell adhesion can determine cell cycle progression. © The Company of Biologists Limited 2001 2001 Tyrosine kinase Signal transduction Growth control Cell adhesion Proliferation of mammalian cells is tightly regulated by multiple...
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Journal Articles
J Cell Sci (1995) 108 (1): 225–233.
Published: 1 January 1995
... by the platelet-derived growth factor and insulin receptors. The effects of lysophosphatidic acid on the Swiss 3T3 actin cytoskeleton can be blocked by the tyrosine kinase inhibitor, tyrphostin. Since tyrphostin does not inhibit the effects of microinjected rho protein, we conclude that lysophosphatidic acid...
Journal Articles
J Cell Sci (1994) 107 (3): 417–425.
Published: 1 March 1994
... FGF receptor tyrosine kinase mesenchyme condensation brain development amphibian During the last few years significant progress has been made in the understanding of mechanisms of mesoderm formation in amphibian embryos, primarily due to the discovery that peptide growth factors belonging...
Journal Articles
J Cell Sci (1994) 1994 (Supplement_18): 121–126.
Published: 1 January 1994
...Lewis C. Cantley; Zhou Songyang ABSTRACT SH2 domains and SH3 domains, found in a number of protein-tyrosine kinases and substrates of protein-tyrosine kinases, provide specificity in downstream signaling. Both of these domains bind to relatively short linear sequences of peptides to provide...
Journal Articles
J Cell Sci (1993) 106 (4): 1211–1220.
Published: 1 December 1993
... was phosphorylated on serine and tyrosine residues, suggesting that the activation of protein kinase C also stimulated tyrosine kinase activity. p37 did not precipitate with annexin I or II antibodies. These results show that sheep tracheal cilia contain protein kinase C activity and that activated protein kinase C...
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Journal Articles
J Cell Sci (1993) 105 (3): 629–636.
Published: 1 July 1993
... was investigated by western blot analysis and its tyrosine kinase activity was measured concomitantly. In mononuclear cytotrophoblasts, pp60 c- src was localized at cell-matrix contacts and during the aggregation of cytotrophoblasts, pp60 c- src was distributed on the cell surface at points of cell-cell contact...
Journal Articles
Journal Articles
J Cell Sci (1991) 99 (2): 207–211.
Published: 1 June 1991
... is associated with tyrosine phosphorylation, the signal transduction pathways and the mechanism by which oncogenic tyrosine kinases induce cell growth and neoplastic changes remain elusive ( Jove and Hanafusa, 1987 ; Yarden and Ullrich, 1988 ). The acutely transforming avian sarcoma viruses have been invaluable...
Journal Articles