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Keywords: Type I IFN
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Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2021) 134 (5): jcs246421.
Published: 23 April 2020
... cells from PTP1B-knockout mice secrete lower amounts of type I interferon (IFN) than cells from wild-type mice. In contrast, secretion of the proinflammatory cytokines TNFα and IL6 was unaltered. While PTP1B deficiency did not affect Ifnb1 transcription, type I IFN accumulated in macrophages, suggesting...
Includes: Supplementary data