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Keywords: Type 2 diabetes
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Journal Articles
J Cell Sci (2016) 129 (12): 2368–2381.
Published: 15 June 2016
... by The Company of Biologists Ltd 2016 Summary: Selective molecules bearing a kinked acyl chain can counter membrane disorders in lipointoxication-related diseases by acting as nanospacers. Early secretory pathway Lipointoxication Membrane interfacial surface voids Type 2 diabetes...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (14): 2308–2318.
Published: 15 July 2008
... L. Eizirik; Miriam Cnop Free fatty acids (FFA) cause apoptosis of pancreatic β-cells and might contribute to β-cell loss in type 2 diabetes via the induction of endoplasmic reticulum (ER) stress. We studied here the molecular mechanisms implicated in FFA-induced ER stress initiation and apoptosis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2003) 116 (1): 73–79.
Published: 01 January 2003
...-regulated insulin release system in adipocytes by introducing the preproinsulin gene. Type-2 diabetes results from β-cell dysfunction and insulin resistance, or a combination of both, which can lead to diabetic complications such as retinopathy, nephropathy and neuropathy( Lilloja et al., 1993 ; Ward...