1-4 of 4
Keywords: Tumour suppression
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
J Cell Sci (2011) 124 (11): 1785–1793.
Published: 1 June 2011
... of sensitivity to ErbB-targeted therapeutics. Although the LRIG1 gene maps to chromosome 3p14, a region frequently deleted in human tumours, conclusive genetic evidence implicating a role for LRIG1 in tumour suppression is not yet available. Nevertheless, a number of reports suggest that loss of LRIG1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2001) 114 (20): 3591–3598.
Published: 15 October 2001
... biological role that explains tumour suppression by the BRCA proteins? At least in the case of BRCA1, cancer-associated mutations affecting a number of different regions spanning the length of the protein have the common property of being unable to reconstitute DSB repair when expressed in BRCA1-deficient...
Journal Articles
J Cell Sci (1994) 1994 (Supplement_18): 1–5.
Published: 1 January 1994
... of Biologists Limited 1994 1994 Wilms’ tumour WT1 transcriptional repression tumour suppression zinc finger ...
Journal Articles
J Cell Sci (1988) 1988 (Supplement_10): 171–180.
Published: 1 February 1988
... the fragmentary but firm evidence that shows the existence of such mechanisms. Tumour-suppressing genes have been detected in the following systems: (i) Fusion of normal and malignant cells leads to the suppression of the tumorigenic phenotype in the majority of the combinations where the hybrid maintains...