... pEGFR levels, cell invasion, migration and tumor metastasis. Furthermore, we found that MMP2, MMP11, pErk, and ADAM15 were upregulated, whereas TIMP2 was downregulated; all of which supported the roles of miR-24 in tumor invasion and metastasis. Our results suggest that miR-24 plays a key role in breast...

... of bioactive molecules such as proteins, RNAs and microRNAs, they are now thought to have vital roles in tumor invasion and metastases, inflammation, coagulation, and stem-cell renewal and expansion. This Commentary summarizes recent literature on the properties and biogenesis of microvesicles...

... for prevention of MMT in strategies for chemoprevention of tumor invasion. TGFβ1 was shown earlier to be a potent inducer of IL-6 mRNA and protein in primary human lung fibroblasts (Eickelberg et al., 1999) and of VEGF in human dermal fibroblasts (Trompezinski et al., 2000). Furthermore, tumor-derived TGFβ1...