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Keywords: Transmigration
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Journal Articles
In collection:
Cell Migration
J Cell Sci (2021) 134 (7): jcs255653.
Published: 01 April 2021
..., including rolling, adhesion, crawling, diapedesis and sub-endothelial crawling. Nowadays, the role of the endothelium in transmigration is increasingly appreciated. It has been established that leukocyte exit sites on the endothelium and in the pericyte layer are in fact not random but instead may...
Journal Articles
J Cell Sci (2021) 134 (3): jcs250340.
Published: 08 February 2021
... of transmigrating cells was performed using time-lapse epifluorescence microscopy – where HL-60 cells would be serially imaged in phase and then fluorescence channels (to detect either PECAM-1–GFP or L-selectin–RFP). Images were acquired once every 4 s for primary human neutrophils (phase only) and every 50 s...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (13): jcs215541.
Published: 04 July 2018
... within transmigrated pseudopods re-establishes their binding to targets, such as L-selectin. Knockdown of ezrin, but not moesin, severely impaired the recruitment of monocytes to activated endothelial monolayers under flow, suggesting that this protein plays a unique role in the early recruitment process...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (13): 2221–2230.
Published: 01 July 2015
... cell stiffness and its relevance for leukocyte adhesion, crawling and transendothelial migration. Adhesion Endothelium ICAM1 Mechanotransduction Transmigration Single-cell organisms, circulating cells and cells in tissues respond to a wide range of stimuli with polarization...
Journal Articles
J Cell Sci (2014) 127 (20): 4470–4482.
Published: 15 October 2014
... and the endothelium. Leukocyte β2-integrins bind to endothelial intercellular adhesion molecule 1 (ICAM-1), which allows leukocyte spreading, crawling and transendothelial migration. Leukocytes scan the vascular endothelium for permissive sites to transmigrate, which suggests that there is apical membrane...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (22): 3842–3850.
Published: 15 November 2008
... in ECs was also involved in monocyte transmigration. Collectively, our study identifies a role of EphBR-ephrinB interactions as a new step in the cascade of events leading to monocyte adhesion and transmigration through the vascular endothelium. References Adams, R. H. ( 2002 ). Vascular...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (22): 4634–4643.
Published: 15 November 2006
.... Using mixed cultures of wild-type and PrP C -deficient mouse brain endothelial cells, we observed that PrP C accumulation at cell-cell contacts was probably dependent on homophilic interactions between adjacent cells. Moreover, we report that anti-PrP C antibodies unexpectedly inhibited transmigration...
Journal Articles
J Cell Sci (2005) 118 (9): 2067–2076.
Published: 01 May 2005
... intracellular stores to the cell surface of transmigrating mouse neutrophils, although these events occur via mechanisms dependent on and independent of platelet/endothelial-cell adhesion molecule 1 (PECAM-1, CD31), respectively. Despite different regulatory mechanisms, blockade of α6 integrins or NE inhibited...