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Keywords: Transforming growth factor
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Journal Articles
Jessica L. Sacco, Zachary T. Vaneman, Ava Self, Elix Sumner, Stella Kibinda, Chinmay S. Sankhe, Esther W. Gomez
Journal:
Journal of Cell Science
J Cell Sci (2024) 137 (22): jcs262190.
Published: 25 November 2024
..., it is not clear how chemical and mechanical signals are integrated to regulate EZH2 and gene expression. We show that culture of cells on stiff matrices in concert with transforming growth factor (TGF)-β1 promotes nuclear localization of EZH2 and an increase in the levels of the corresponding histone modification...
Includes: Supplementary data