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Keywords: Transferrin receptor
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Journal Articles
J Cell Sci (2014) 127 (20): 4457–4469.
Published: 15 October 2014
... show that mutation of the N-glycan linked to N727 in the basolateral marker transferrin receptor (TfR) or knockdown of galectin-4 inhibits TfR transcytosis to apical recycling endosomes and the apical plasma membrane, and promotes TfR lysosomal targeting and subsequent degradation. Our results report...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (1): 60–71.
Published: 01 January 2014
... proteins. On the one hand, p0071 depletion induced a perinuclear accumulation of Rab11, suggesting a role of p0071 in the anterograde transport of Rab11 from the pericentrosomal region to the plasma membrane but not in retrograde transport. p0071 as well as Rab11 depletion increased transferrin receptor...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (13): 2798–2809.
Published: 01 July 2013
...Hideaki Fujita; Yukie Iwabu; Kenzo Tokunaga; Yoshitaka Tanaka Summary The transferrin receptor (TfR) mediates the uptake of transferrin (Tf)-bound iron from the plasma into the cells of peripheral tissues. The TfR continuously recycles between the plasma membrane and early/recycling endosomes. TfR...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (17): 4049–4057.
Published: 01 September 2012
... remains unknown. We show here that, in addition to causing tubulation of recycling endosomes, Rab11 depletion gives rise to accumulation of recycling carriers containing endocytosed transferrin and transferrin receptor beneath the plasma membrane. We also show that the carriers are transported from...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (7): 1168–1177.
Published: 01 April 2007
... to inhibit basal Glut4 retention. Neither wild-type nor S10D synapsin redistributed Glut4. S10A synapsin did not elevate surface levels of the transferrin receptor in adipocytes or Glut4 in fibroblasts. Therefore, S10A synapsin is inhibiting the specialized process of basal intracellular retention of Glut4...
Includes: Supplementary data
Journal Articles
J Cell Sci (2005) 118 (23): 5499–5511.
Published: 01 December 2005
...Kevin J. Schwartz; Ronald F. Peck; Ngii N. Tazeh; James D. Bangs Progression of GPI-anchored proteins in bloodstream African trypanosomes correlates with GPI-valence: homodimeric VSG (2 GPI) is a surface protein; heterodimeric transferrin receptor (1 GPI) localizes in the flagellar pocket...
Journal Articles
J Cell Sci (2002) 115 (12): 2505–2515.
Published: 15 June 2002
... the transferrin receptor (TfR) is found associated with the vesicles. Interestingly, this cell line has been shown to possess high amounts of Rab11 compared with other Rab proteins. To assess the regulation of transferrin receptor release via exosome secretion by Rab11 in this cell type, K562 cells were stably...
Journal Articles
J Cell Sci (2002) 115 (5): 991–1004.
Published: 01 March 2002
... cells. A dominant negative approach using a GFP-Myo5c tail construct in HeLa cells reveals that the Myo5c tail selectively colocalizes with and perturbs a membrane compartment containing the transferrin receptor and rab8. Transferrin also accumulates in this compartment, suggesting that Myo5c...
Includes: Supplementary data
Journal Articles
J Cell Sci (1993) 1993 (Supplement_17): 93–100.
Published: 01 December 1993
... of SV proteins is observed even at stages when the transferrin receptor, a protein that is present in epithelial cells only at the basolateral surface, is already restricted to dendrites. This indicates that, in immature neurons, SV proteins are not selectively targeted to axons...