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1-2 of 2
Keywords: Topoisomerase I
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Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2011) 124 (23): 3967–3979.
Published: 1 December 2011
... in U-2 OS (WRN wild type) and isogenic cells stably expressing WRN-targeted shRNA (WRN knockdown). The results of our studies suggest that WRN has a crucial role in inducing an S-phase checkpoint in cells exposed to the topoisomerase I inhibitor campthothecin (CPT), but not in cells exposed...
Includes: Supplementary data
Journal Articles
Segregation of nucleolar components coincides with caspase-3 activation in cisplatin-treated HeLa cells
Available to PurchaseMarcel Horký, Gabriele Wurzer, Vladimír Kotala, Milan Anton, Bólivoj Vojtěsěk, Jiří Vácha, Jozefa Wesierska-Gadek
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (4): 663–670.
Published: 15 February 2001
... hours post treatment was characterized by degradation of other nucleolar and nuclear proteins such as nuclear lamins, topoisomerase I and B23. In conclusion, remarkable segregation of nucleolar argyrophilic proteins, nucleolar RNA and a simultaneous activation of the cascade of caspases markedly...
