... structures in 3D. These results uncover that Δ133p53 isoforms coordinate expression and deposition of organ-specific ECM molecules that are critical for maintenance of tissue architecture and function. We thank Drs Alex Davies, Richard Schwarz, Joni Mott, and Weiguo Zhang for critical reading...

...Pierre-Alexandre Vidi; Gurushankar Chandramouly; Matthew Gray; Lei Wang; Er Liu; Joseph J. Kim; Vassilis Roukos; Mina J. Bissell; Prabhas V. Moghe; Sophie A. Lelièvre Epithelial tissue morphogenesis is accompanied by the formation of a polarity axis – a feature of tissue architecture...

... gland have been that carcinogens induce neoplasia by causing mutations in the DNA of the epithelial cells and that the alterations of tissue architecture observed in neoplasms are a consequence of this primary mutational event. Here, we use a rat mammary tissue recombination model and the chemical...

...P. G. Natali; M. R. Nicotra; A. Bigotti; C. De Martino ABSTRACT The 6 / 4 integrin, of undefined receptor activity, has been shown to be expressed in a variety of murine epithelial cells. To gain information on the role of this heterodimer in tissue architecture as well as in malignant...