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Keywords: Thrombin
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Journal Articles
J Cell Sci (2021) 134 (17): jcs258823.
Published: 08 September 2021
... than other sensors of this type, and this sensor enables the observation of endogenous Rho activity in cultured cells. Biosensor Rho GTPase Endothelial cell Thrombin Rho Nederlandse Organisatie voor Wetenschappelijk Onderzoek http://dx.doi.org/10.13039/501100003246 ALWOP.306...
Includes: Supplementary data
Journal Articles
J Cell Sci (2021) 134 (8): jcs254888.
Published: 22 April 2021
... by The Company of Biologists Ltd 2021 Summary: The α-arrestin ARRDC3 is a multi-functional tumor suppressor that distinctly regulates GPCR trafficking and TAZ-dependent Hippo signaling in metastatic triple negative breast cancer. Hippo pathway PAR1 PAR2 Thrombin S1P LPA Basal-like...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (9): 1435–1443.
Published: 01 May 2008
...Anne-Catherine Feutz; Yann Barrandon; Denis Monard In hair follicles, dermal papilla (DP) and dermal sheath (DS) cells exhibit striking levels of plasticity, as each can regenerate both cell types. Here, we show that thrombin induces a phosphoinositide 3-kinase (PI3K)-Akt pathway-dependent...
Includes: Supplementary data
Journal Articles
J Cell Sci (2007) 120 (6): 921–928.
Published: 15 March 2007
... Thrombin Trafficking Coagulant protease Protease-activated receptors (PARs) are G-protein-coupled receptors (GPCRs) that signal in response to extracellular proteases. There are four PARs encoded in the mammalian genome. PAR1, the prototype for this family, transmits cellular responses...
Journal Articles
J Cell Sci (2003) 116 (12): 2399–2408.
Published: 15 June 2003
... thrombin is a potent cell modulator obligately produced at the site of clot formation, we hypothesized that the amount of cell-surface A2 and p11 might be altered by thrombin with consequent effects on plasmin generation. In support of this hypothesis, immunofluorescence microscopy and hydrophilic...
Journal Articles
J Cell Sci (2002) 115 (12): 2475–2484.
Published: 15 June 2002
...Valérie Vouret-Craviari; Christine Bourcier; Etienne Boulter; Ellen Van Obberghen-Schilling Soluble mediators such as thrombin and sphingosine-1-phosphate regulate morphological changes in endothelial cells that affect vascular permeability and new blood vessel formation. Although these ligands...