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Keywords: Tetraploidy
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Journal Articles
J Cell Sci (2008) 121 (23): 3859–3866.
Published: 01 December 2008
... but aneuploid karyotype. Both CIN and stable aneuploidy are commonly observed in cancers. Recently, it has been proposed that an increased number of chromosome sets can promote cell transformation and give rise to an aneuploid tumor. Here, we review how tetraploidy can occur and describe the cellular responses...
Journal Articles
J Cell Sci (2007) 120 (20): 3633–3639.
Published: 15 October 2007
...., Nitta, M., Ivanova, E. V., Bronson, R. T. and Pellman, D. ( 2005 ). Cytokinesis failure generating tetraploids promotes tumorigenesis in p53-null cells. Nature 437 , 1043 -1047. Ganem, N. J., Storchova, Z. and Pellman, D. ( 2007 ). Tetraploidy, aneuploidy and cancer. Curr. Opin. Genet. Dev...
Includes: Multimedia, Supplementary data