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Keywords: Testis
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Journal Articles
Eugenia Guida, Valentina Tassinari, Ambra Colopi, Federica Todaro, Valeriana Cesarini, Benedetto Jannini, Manuela Pellegrini, Flavia Botti, Gabriele Rossi, Pellegrino Rossi, Emmanuele A. Jannini, Susanna Dolci
Journal:
Journal of Cell Science
J Cell Sci (2022) 135 (8): jcs259375.
Published: 20 April 2022
... acid-induced differentiation . Stem Cells 26 , 2928 - 2937 . 10.1634/stemcells.2008-0134 De Felici , M. and Dolci , S. ( 2013 ). From testis to teratomas: a brief history of male germ cells in mammals . Int. J. Dev. Biol. 57 , 115 - 121 . 10.1387/ijdb.130069md...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2018) 131 (19): jcs221481.
Published: 8 October 2018
... MARVEL transmembrane domain containing) protein family remain to be determined. In this study, we focused on the testis-specific mouse CMTM gene cluster ( Cmtm1 , Cmtm2a and Cmtm2b ) and generated CRISPR/Cas9-mediated mutant mice to examine their physiological functions. Although Cmtm1 mutant mice were...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2014) 127 (22): 4870–4882.
Published: 15 November 2014
...Ka-Wai Mok; Dolores D. Mruk; C. Yan Cheng ABSTRACT Mammalian target of rapamycin complex 1 (mTORC1) is an emerging regulator of blood–tissue barriers that utilizes ribosomal protein S6 (rpS6) as the downstream signaling molecule. To explore the role of rpS6 in blood–testis barrier (BTB) function...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2012) 125 (23): 5677–5689.
Published: 1 December 2012
...Xiang Xiao; C. Yan Cheng; Dolores D. Mruk Summary The mechanism underlying the movement of preleptotene/leptotene spermatocytes across the blood–testis barrier (BTB) during spermatogenesis is not well understood largely owing to the fact that the BTB, unlike most other blood–tissue barriers...
Includes: Supplementary data
Journal Articles
Natacha Dreumont, Cyril F. Bourgeois, Fabrice Lejeune, Yilei Liu, Ingrid E. Ehrmann, David J. Elliott, James Stévenin
Journal:
Journal of Cell Science
J Cell Sci (2010) 123 (1): 40–50.
Published: 1 January 2010
... of a testis-enriched exon from the Acinus gene, whereas 9G8 and Tra2-β repressed this exon. We propose that hRBMY associates with regions of the nucleus enriched in nascent RNA and participates in the regulation of specific splicing events in the germline by modulating the activity of constitutively expressed...
Includes: Supplementary data
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (24): 5835–5845.
Published: 15 November 2004
...Nanaho Fukuda; Kentaro Yomogida; Masaru Okabe; Kazushige Touhara Although a subset of the olfactory receptor (OR) gene family is expressed in testis, neither their developmental profile nor their physiological functions have been fully characterized. Here, we show that MOR23 (a mouse OR expressed...
Journal Articles
Céline Fiorini, Baharia Mograbi, Laurent Cronier, Isabelle Bourget, Xavier Decrouy, Marielle Nebout, Bernard Ferrua, André Malassine, Michel Samson, Patrick Fénichel, Dominique Segretain, Georges Pointis
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (20): 4665–4672.
Published: 15 September 2004
... the seminiferous tubules in the testis. In contrast to the majority of connexins, connexin33 was unphosphorylated. Immunoprecipitation experiments revealed that connexin33 physically interacted with connexin43, mainly with the phosphorylated P1 isoform of connexin43 but not with connexin26 and connexin32, two...
Journal Articles
Ruben Nogueiras, M. Luz Barreiro, Jorge E. Caminos, Francisco Gaytán, Janne S. Suominen, Victor M. Navarro, Felipe F. Casanueva, Enrique Aguilar, Jorma Toppari, Carlos Diéguez, Manuel Tena-Sempere
Journal:
Journal of Cell Science
J Cell Sci (2004) 117 (15): 3247–3257.
Published: 1 July 2004
... testis. Resistin gene expression was demonstrated in rat testis throughout postnatal development, with maximum mRNA levels in adult specimens. At this age, resistin peptide was immunodetected in interstitial Leydig cells and Sertoli cells within seminiferous tubules. Testicular expression of resistin...
Journal Articles
Nina Korsisaari, Derrick J. Rossi, Anders Paetau, Patrick Charnay, Mark Henkemeyer, Tomi P. Mäkelä
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (22): 4275–4284.
Published: 15 November 2002
... in the absence of Mat1 ( Rossi et al., 2001 ). Ablation of Mat1 in mitotic cells was analyzed in the testis, where Krox-20 is expressed in the mitotic germ cells upon sexual maturation. It was noted that this cell population was rapidly rendered non-viable upon ablation of Mat1 indicating...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2002) 115 (17): 3491–3496.
Published: 1 September 2002
...Peter J. O'Shaughnessy; Heather Johnston; Louise Willerton; Paul J. Baker During testicular development, fetal and adult populations of Leydig cells arise sequentially. Previous studies have shown that androgen action is required for normal steroidogenic activity in the mouse testis. Therefore...
Journal Articles
Barbara Janssens, Steven Goossens, Katrien Staes, Barbara Gilbert, Jolanda van Hengel, Cecile Colpaert, Erik Bruyneel, Marc Mareel, Frans van Roy
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (17): 3177–3188.
Published: 1 September 2001
... of the cadherin/catenin complex to the actin cytoskeleton via α-catenin. To date, it is not clear how different cell types achieve the variable strength of cell-cell adhesion clearly needed in a multicellular organism. Here, we report the cloning and molecular characterization of αT(testis)-catenin, a novel human...
Journal Articles
Juliette Longin, Patricia Guillaumot, Marie-Agnès Chauvin, Anne-Marie Morera, Brigitte Le Magueresse-Battistoni
Journal:
Journal of Cell Science
J Cell Sci (2001) 114 (11): 2125–2134.
Published: 1 June 2001
...Juliette Longin; Patricia Guillaumot; Marie-Agnès Chauvin; Anne-Marie Morera; Brigitte Le Magueresse-Battistoni Metalloproteases (MMPs) are likely to be involved in the restructuring events occurring in the testis throughout development. We here demonstrate that membrane-type 1 (MT1)-MMP...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (4): 673–682.
Published: 15 February 2000
... report here evidence for an involvement of mammalian SMC1 and SMC3 proteins in meiosis. Immunofluorescence analysis of testis sections showed intense chromatin association in meiotic prophase cells, weaker staining in round spermatids and absence of the SMC proteins in elongated spermatids...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (1): 161–168.
Published: 1 January 2000
...Wei Yan; Janne Suominen; Jorma Toppari ABSTRACT Stem cell factor (SCF) plays an important role in migration, adhesion, proliferation, and survival of primordial germ cells and spermatogonia during testicular development. However, the function of SCF in the adult testis is poorly described. We have...
Journal Articles
Jean-Philippe Stéphan, Nathalie Melaine, Eric Ézan, Harri Hakovirta, Simon Maddocks, Jorma Toppari, Danielle-Hélène Garnier, Joanna Wdzieczak-Bakala, Bernard Jégou
Journal:
Journal of Cell Science
J Cell Sci (2000) 113 (1): 113–121.
Published: 1 January 2000
... proliferation. The present study was aimed at investigating the presence and the role of AcSDKP in rat testis. Specific immunoreactivity was always observed in the interstitial tissue at all stages of testicular development and in elongated spermatids at 45 days of age and in adults. In accordance...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (20): 3455–3462.
Published: 15 October 1999
...Charles Pineau; Suzan McCool; Marc J. Glucksman; Bernard Jégou; Adrian R. Pierotti ABSTRACT Thimet oligopeptidase (TOP:E.C. 3.4.24.15) is a thiol sensitive metalloendopeptidase which is widely distributed and active in most tissues including testis, brain and pituitary. In the median eminence...
Journal Articles
Andreas Meinhardt, Michael Bacher, Moira K. O’Bryan, James R. McFarlane, Con Mallidis, Christof Lehmann, Christine N. Metz, David M. de Kretser, Richard Bucala, Mark P. Hedger
Journal:
Journal of Cell Science
J Cell Sci (1999) 112 (9): 1337–1344.
Published: 1 May 1999
[email protected] ) † Present address: Department of Physiology, University of New England, Armidale, NSW 2351, Australia 18 02 1999 08 04 1999 © 1999 by Company of Biologists 1999 Testis MIF EDS Macrophage migration inhibitory factor (MIF) was originally...
Journal Articles
Valérie Chesneau, Annik Prat, Dominique Segretain, Véronique Hospital, Alain Dupaix, Thierry Foulon, Bernard Jégou, Paul Cohen
Journal:
Journal of Cell Science
J Cell Sci (1996) 109 (11): 2737–2745.
Published: 1 November 1996
.... Although present in brain and several other tissues, NRD convertase is particularly abundant in testis, where its expression appeared to be restricted to germ cells. Low levels of both mRNA and its corresponding protein were detected early in spermatogenesis. However, a marked accumulation of the protein...
Journal Articles
A novel member of the dynamin family of GTP-binding proteins is expressed specifically in the testis
Journal:
Journal of Cell Science
J Cell Sci (1993) 105 (1): 1–5.
Published: 1 May 1993
... 848 amino acids and has great sim-ilarity with brain dynamin and the shibire product. Northern blot analysis and in situ hybridization revealed its expression to be specific to the seminiferous tubules in the testis. Dynamin-2 (testis type dynamin) was expressed in germ-cell-depleted testis as well...
Journal Articles
Journal:
Journal of Cell Science
J Cell Sci (1989) 94 (1): 61–71.
Published: 1 September 1989
...B. K. A. Rasheed; E. C. Whisenant; R. D. Ghai; V. E. Papaioannou; Y. M. Bhatnagar ABSTRACT An Hl histone variant, H1a, has been isolated and purified from the mouse testis. Biochemical and amino acid analyses indicate its similarity with the rat testis H1a. Specific antibodies against the purified...