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Keywords: TRPML
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Journal Articles

TRP channels in health and disease at a glance

Lixia Yue, Haoxing Xu
Journal: Journal of Cell Science
J Cell Sci (2021) 134 (13): jcs258372.
https://doi.org/10.1242/jcs.258372
Published: 13 July 2021
..., including TRPC (canonical), TRPV (vanilloid), TRPM (melastatin), TRPA (ankyrin), TRPML (mucolipin) and TRPP (polycystin), are widely expressed in different cells and tissues. TRPs exhibit a variety of unique features that not only distinguish them from other superfamilies of ion channels, but also confer...
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Includes: Supplementary data
Journal Articles

LAPTMs regulate lysosomal function and interact with mucolipin 1: new clues for understanding mucolipidosis type IV

Silvia Vergarajauregui, Jose A. Martina, Rosa Puertollano
Journal: Journal of Cell Science
J Cell Sci (2011) 124 (3): 459–468.
https://doi.org/10.1242/jcs.076240
Published: 1 February 2011
... in MLIV pathogenesis. * Author for correspondence ( [email protected] ) 8 10 2010 © 2011. 2011 Mucolipin LAPTM TRPML MLIV Lysosomes Mucolipidosis type IV (MLIV) is an autosomal recessive disorder characterized by severe neurologic and ophthalmologic abnormalities...
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Includes: Supplementary data
Journal Articles

Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy

David A. Zeevi, Shaya Lev, Ayala Frumkin, Baruch Minke, Gideon Bach
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (18): 3112–3124.
https://doi.org/10.1242/jcs.067330
Published: 15 September 2010
...David A. Zeevi; Shaya Lev; Ayala Frumkin; Baruch Minke; Gideon Bach The mucolipin (TRPML) subfamily of transient receptor potential (TRP) cation channels consists of three members that play various roles in the regulation of membrane and protein sorting along endo-lysosomal pathways. Loss...
View articletitled, Heteromultimeric TRPML channel assemblies play a crucial role in the regulation of cell viability models and starvation-induced autophagy
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Includes: Supplementary data