1-5 of 5
Keywords: TRPC6
Close
Follow your search
Access your saved searches in your account

Would you like to receive an alert when new items match your search?
Close Modal
Sort by
Journal Articles
In collection:
Mechanobiology
J Cell Sci (2019) 132 (23): jcs238360.
Published: 10 December 2019
... mammalian subfamilies. We found that these TRP channels were insensitive to short membrane stretches in cellular systems. Furthermore, we purified TRPC6 and demonstrated its insensitivity to stretch in liposomes, an artificial bilayer system free from cellular components. Additionally, we demonstrated...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (17): 3317–3329.
Published: 1 September 2015
... under hypoxia. TRPC6 was rapidly activated by IGF-1R–PLCγ–IP 3 R pathway upon hypoxia. Inhibition of TRPC6 enhanced the levels of α-ketoglutarate and promoted hydroxylation of HIF-1α to suppress HIF-1α accumulation without affecting its transcription or translation. Dimethyloxalylglycine N...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (19): 4159–4171.
Published: 1 October 2014
...Hiroya Takada; Kishio Furuya; Masahiro Sokabe ABSTRACT Cutaneous wound healing is accelerated by exogenous mechanical forces and is impaired in TRPC6-knockout mice. Therefore, we designed experiments to determine how mechanical force and TRPC6 channels contribute to wound healing using HaCaT...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (17): 4026–4035.
Published: 1 September 2012
... of Biologists Ltd 2012 NFAT TrpC6 c-Met Drug screen Ion flux Metastasis The G-protein coupled receptors (GPCRs) constitute the largest family of protein with almost a thousand members ( Fredriksson et al., 2003 ; Takeda et al., 2002 ). They play a central role in regulating various...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (17): 4001–4013.
Published: 1 September 2012
... that block HGF-induced scattering, including a calcium channel blocker. We show that HGF stimulation results in sudden and transient increases in ion channel influxes at the plasma membrane. Although multiple channels occur in the membranes of our model system, we find that TrpC6 is specifically required...
Includes: Supplementary data