...Lixia Yue; Haoxing Xu ABSTRACT The transient receptor potential (TRP) channel superfamily consists of a large group of non-selective cation channels that serve as cellular sensors for a wide spectrum of physical and environmental stimuli. The 28 mammalian TRPs, categorized into six subfamilies...

... of the controversial cilia mechanotransduction hypothesis, by providing different facts that support and oppose this hypothesis. Low Reynolds number Mechanotransduction Transient receptor potential channel TRP channels Agence Nationale de la Recherche 10.13039/501100001665 ANR-15-CE13-0015-01...

... that the original work is properly attributed. Summary: The endolysosomal ion channel TRP mucolipin 1 was thought to mediate local Ca 2+ signals. However, as reported here, it can also mediate global elevations in Ca 2+ . Ca 2+ Lysosomes TRP channels Endoplasmic reticulum Biotechnology...

...Sukanya Sengupta; Thomas R. Barber; Hongai Xia; Donald F. Ready; Roger C. Hardie Summary The prototypical transient receptor potential (TRP) channel is the major light-sensitive, and Ca 2+ -permeable channel in the microvillar photoreceptors of Drosophila . TRP channels are activated following...

... TRPML-regulated mechanisms. * These authors contributed equally to this work ‡ Author for correspondence ( [email protected] ) 5 6 2010 © 2010. 2010 Mucolipin TRPML Ion channel heteromultimerization TRP channels Starvation-induced autophagy The mucolipins...

...-u.ac.jp ) 18 12 2009 © 2010. 2010 B-cell receptor Ca 2+ signaling Diacylglycerol PKCβ TRP channels Calcium signaling evoked by stimulation of plasma membrane (PM) receptors linked to phospholipase C (PLC) plays a central role in lymphocyte activation through production...

...Michelle A. Cronin; Minh-Ha Lieu; Susan Tsunoda Transient receptor potential (TRP) channels across species are expressed in sensory receptor cells, and often localized to specialized subcellular sites. In Drosophila photoreceptors, TRP-like (TRPL) channels are localized to the signaling compartment...

... that lead to TRP channel activation in vivo remain unclear. Recently, the lipid products of phosphoinositide hydrolysis (such as diacylglycerol and its metabolites) have been implicated in activating TRP channels in both Drosophila and mammals. In Drosophila photoreceptors, lack of diacylglycerol kinase...