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Keywords: TIR domainClose
Journal: Journal of Cell Science
J Cell Sci (2010) 123 (2): 256–265.
Published: 15 January 2010
..., a step mediated by homotypic Toll-IL-1 receptor (TIR) domain interactions. Four TIR-containing TLR adaptor molecules are described, all of which are susceptible to modification and strict regulation. For example, caspase-1 is reported to cleave the TLR adaptor Mal at position D198, an event...
Includes: Supplementary data