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Keywords: TGF-β1
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J Cell Sci (2010) 123 (24): 4321–4331.
Published: 15 December 2010
... in the induction of EMT. The use of specific inhibitors, a dominant-negative p38 mutant and lentiviral silencing of p38α demonstrated that p38 promotes E-cadherin expression both in untreated cells and in cells co-stimulated with the EMT-inducing stimuli transforming growth factor (TGF)-β1 and interleukin (IL)-1β...
Includes: Supplementary data
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J Cell Sci (2002) 115 (15): 3181–3191.
Published: 1 August 2002
...Guangsheng Fan; Xiaoming Ma; Betsy T. Kren; Clifford J. Steer E2F is an important target of the retinoblastoma protein (pRb) and plays a critical role in G 1 /S progression through the cell cycle. TGF-β1 arrests HuH-7 cells in G 1 by suppressing phosphorylation of pRb and induces apoptosis...
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J Cell Sci (2001) 114 (21): 3905–3914.
Published: 1 November 2001
... and/or focalization of PAI-1 and its protease target PAs, thereby influencing cell migration by barrier proteolysis and/or ECM adhesion modulation. TGF-β1, in particular, is an effective inducer of matrix deposition/turnover, cell locomotion and PAI-1 expression. Therefore, the relationship between motility and PAI-1...
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J Cell Sci (1992) 103 (2): 521–529.
Published: 1 October 1992
...) and by the absence of αsmooth muscle actin (α-SM actin) may be induced to express the latter when exposed to TGF-β1. FVIII was detected by immunofluorescence, α-SM actin was detected by immunofluorescence and immunoblotting. The number of cells expressing α-SM actin increased with time of incubation with TGF-β1...
Journal Articles
J Cell Sci (1989) 94 (3): 567–575.
Published: 1 November 1989
... synthesis and cell division occurred in both types of fibroblasts. This effect was either reduced in the HSF cells or enhanced in the 3Y1 cells by the addition of platelet lysate. TGF-β1 added to the fresh medium containing 90% PPP also inhibited the induction of DNA synthesis in the HSF cells...