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Keywords: Systems biology
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Journal Articles
J Cell Sci (2013) 126 (9): 1913–1921.
Published: 1 May 2013
... computationally. * Authors for correspondence ( kjanes@virginia.edu ; lauffen@mit.edu ) © 2013. Published by The Company of Biologists Ltd 2013 Cell signalling Computational biology Systems biology A decade ago, we welcomed the first signalling-network models that were strongly grounded...
Journal Articles
J Cell Sci (2012) 125 (17): 4103–4113.
Published: 1 September 2012
.... G. ( 2007 ). Systems biology analysis of G protein and MAP kinase signaling in yeast.   Oncogene   26 , 3254 – 3266 . 10.1038/sj.onc.1210416 Hohmann   S. ( 2009 ). Control of high osmolarity signalling in the yeast Saccharomyces cerevisiae.   FEBS Lett.   583 , 4025 – 4029...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (1): 82–90.
Published: 1 January 2011
... activity in breast cancer cells . Nat. Cell Biol. 8 , 1398 - 1406 . Systems biology Calcineurin–NFAT signaling pathway RCAN1 Incoherent regulation switch Cardiac hypertrophy Mathematical modeling The calcineurin–nuclear factor of activated T-cells (NFAT) signaling pathway has...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2011) 124 (1): 35–46.
Published: 1 January 2011
... ( nils.johnsson@uni-ulm.de ) 9 9 2010 © 2011. 2011 Constraint interaction network Protein–protein interaction Organelle inheritance Polarized growth Protein kinase Protein phosphatase Systems biology Inactivation of proteins that participate in more than one cellular process leads...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (16): 2834–2843.
Published: 15 August 2010
... mechanistic understanding of physiological TNFα activation of inflammatory responses in cells and tissues. * Author for correspondence ( m.white@liv.ac.uk ) 26 5 2010 © 2010. 2010 NF-κB TNFα Live-cell imaging Stochastic processes Mathematical modelling Systems biology...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (3): 425–435.
Published: 1 February 2009
..., UK 12 10 2008 © The Company of Biologists Limited 2009 2009 Systems biology ERK signaling pathway RKIP Feedback regulation Dynamics Mathematical modeling Signal transduction through the Ras-Raf-MEK-ERK pathway (or ERK pathway for short) is essential for many cellular...
Journal Articles
J Cell Sci (2008) 121 (1): 55–64.
Published: 1 January 2008
... complex from ER membranes owing to GTP hydrolysis by Sar1p. Biophysical modelling Domain formation Membrane traffic Systems biology Protein transport along the secretory pathway is initiated by the formation of small coated vesicles at the endoplasmic reticulum (ER). The core machinery...
Includes: Supplementary data
Journal Articles
In collection:
Metabolism
J Cell Sci (2005) 118 (21): 4947–4957.
Published: 1 November 2005
... networks Network modeling Systems biology © The Company of Biologists Limited 2005 2005 (e-mail: ralbert@phys.psu.edu ) In a scale-free network, small-degree nodes are the most abundant, but the frequency of high-degree nodes decreases relatively slowly. Thus, nodes that have degrees...