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Keywords: Substrate stiffness
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Journal Articles
J Cell Sci (2023) 136 (2): jcs260442.
Published: 31 January 2023
... of substrate stiffness on the Notch signaling pathway in endothelial cells. Using stiffness-tuned polydimethylsiloxane (PDMS) substrates, we show that activity of the Notch signaling pathway inversely correlates with a physiologically relevant range of substrate stiffness (i.e. increased Notch signaling...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (12): jcs216010.
Published: 21 June 2018
... the use of chromatin dynamics to detect cellular force propagation [a technique termed SINK (sensors from intranuclear kinetics)] and investigate the force response of cells to disruption of the monolayer and changes in substrate stiffness. We find that chromatin dynamics change in a substrate stiffness...
Includes: Supplementary data