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Keywords: Subcellular localization
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Journal Articles
J Cell Sci (2012) 125 (14): 3421–3429.
Published: 15 July 2012
... cytoplasmic membrane association of p35–Cdk5 and p39–Cdk5, respectively, through their myristoylation, but it is not clearly understood how the cellular localization is related to different functions. We investigated the role of Cdk5 activity in the subcellular localization of p35–Cdk5 and p39–Cdk5. Cdk5...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (10): 1507–1517.
Published: 15 May 2009
... or CCD. Cldn10a_v1 expression was always found in conjunction with that of Cldn10a ( Fig. 2C ). To determine the subcellular localization of each Cldn10 isoform, N-terminal HA epitope-tagged constructs were generated and transiently expressed in MDCK-II cells. Cells were coimmunolabeled...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (3): 368–377.
Published: 01 February 2009
... 2008 © The Company of Biologists Limited 2009 2009 Amyloid precursor protein (APP) Amyloid precursor-like proteins (APLPs) Subcellular localization Cis and trans dimerization APP processing The amyloid beta (A4) precursor protein (APP) involved in Alzheimer's disease belongs...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2008) 121 (3): 249–253.
Published: 01 February 2008
... 2007 © The Company of Biologists Limited 2008 2008 PTEN Nuclear Subcellular localization Cowden PHTS Bifurcation Phosphatase and tensin homolog (mutated in multiple advanced cancers 1) ( PTEN ), located on 10q23.3, encodes a 403-residue dual-specificity phosphatase that has...
Journal Articles
J Cell Sci (2004) 117 (16): 3519–3529.
Published: 15 July 2004
... and translation. Here, we report that the ETR-3 protein contains multiple regions that control its subcellular localization and are important for its activity as a splicing regulator. We cloned ETR-3 from chicken heart and fused it to the C terminus of green fluorescent protein (GFPcETR3vL). GFPcETR3vL is found...
Journal Articles
J Cell Sci (2004) 117 (14): 3011–3020.
Published: 15 June 2004
... between subtype binding and the subcellular localization of CDC25B. All three subtypes were found to bind to CDC25B. Site-directed mutagenesis studies revealed that 14-3-3β bound exclusively near serine-309 of CDC25B1, which is within a potential consensus motif for 14-3-3 binding. By contrast, 14-3-3σ...
Journal Articles
J Cell Sci (2004) 117 (9): 1773–1784.
Published: 01 April 2004
...Ziv Raviv; Eyal Kalie; Rony Seger The ERK5 signaling cascade acts through sequential activation of MEKK2/3, MEK5 and ERK5 and transmits signals to a variety of stress and mitogenic related targets. In this study we examined the subcellular localization of the components of the ERK5 cascade...