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Keywords: Stress granules
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Journal Articles
J Cell Sci (2024) 137 (4): jcs261326.
Published: 22 February 2024
.... Oxidative stress-induced AGS3 BMCs were distinct from G3BP1 stress granules and from RNA processing BMCs defined by the P-body protein Dcp1a. Immunoblots indicated that cellular stress shifted AGS3, but not the stress granule protein G3BP1 to a membrane pellet fraction following cell lysis. The stress...
Includes: Supplementary data
Journal Articles
J Cell Sci (2023) 136 (14): jcs260590.
Published: 19 July 2023
... that cisplatin ototoxicity might be caused by cisplatin–protein interactions rather than cisplatin–DNA interactions. Two known cisplatin-binding proteins are involved in the stress granule (SG) response. SGs are a pro-survival mechanism involving formation of transient ribonucleoprotein complexes during stress...
Includes: Supplementary data
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J Cell Sci (2022) 135 (18): jcs260282.
Published: 20 September 2022
... granule proteins, keeping them dispersed and thus inhibiting stress granule formation. Upon activation of the Gα subunit of Gq (Gαq), cytosolic PLCβ relocalizes to the membrane, releasing C3PO and stress granule proteins, which in turn promotes activation of C3PO and RNA processing, as well...
Includes: Supplementary data
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Metabolism
J Cell Sci (2020) 133 (16): jcs242487.
Published: 1 September 2020
...Claire L. Riggs; Nancy Kedersha; Pavel Ivanov; Paul Anderson ABSTRACT Stress granules (SGs) and processing bodies (PBs) are membraneless ribonucleoprotein-based cellular compartments that assemble in response to stress. SGs and PBs form through liquid–liquid phase separation that is driven by high...
Includes: Supplementary data
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J Cell Sci (2014) 127 (21): 4692–4701.
Published: 1 November 2014
... (EJC), which is loaded onto spliced mRNAs and plays an essential role in determining their fate. Unlike the three other EJC core components [eIF4AIII, Magoh and Y14 (also known as RBM8A)], MLN51 is mainly located in the cytoplasm, where it plays a key role in the assembly of stress granules...
Includes: Supplementary data
Journal Articles
In collection:
Metabolism
J Cell Sci (2014) 127 (9): 1992–2004.
Published: 1 May 2014
... cerevisiae mRNA-binding proteins mRNA decay Stress response Ribonucleotide particles Stress granules The protein content in a cell at any given time is regulated by transcription, translation and protein degradation. Transcription largely determines the number of mRNA molecules, whereas...
Includes: Supplementary data
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J Cell Sci (2014) 127 (6): 1254–1262.
Published: 15 March 2014
.... Cell   11 , 833 – 848 . 10.1091/mbc.11.3.833 Balagopal   V. , Parker   R. ( 2009 ). Polysomes, P bodies and stress granules states and fates of eukaryotic mRNAs.   Curr. Opin. Cell Biol.   21 , 403 – 408 . 10.1016/j.ceb.2009.03.005 Balagopal   V. , Fluch   L. , Nissan...
Includes: Supplementary data
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J Cell Sci (2013) 126 (18): 4308–4319.
Published: 15 September 2013
... is associated with and inhibited by RNH1 so that random cleavage of cellular RNA is prevented. Under stress conditions, ANG is localized to the cytoplasm and is concentrated in stress granules where it is not associated with RNH1 and thus remains enzymatically active for tiRNA production. By contrast, nuclear...
Includes: Supplementary data