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Keywords: Stress fibers
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Mechanobiology
J Cell Sci (2017) 130 (4): 779–790.
Published: 15 February 2017
...Chiara Tamiello; Maurice Halder; Miriam A. F. Kamps; Frank P. T. Baaijens; Jos L. V. Broers; Carlijn V. C. Bouten ABSTRACT In adherent cells, the relevance of a physical mechanotransduction pathway provided by the perinuclear actin cap stress fibers has recently emerged. Here, we investigate...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2015) 128 (15): 2747–2758.
Published: 1 August 2015
... are unique invaginated membrane nanodomains that play a major role in organizing signaling, lipid homeostasis and adaptation to membrane tension. Caveolae are frequently associated with stress fibers, a major regulator of membrane tension and cell shape. In this Commentary, we discuss recent studies...
Journal Articles
Journal Articles
J Cell Sci (2013) 126 (14): 3021–3030.
Published: 15 July 2013
...Ching-Wei Chang; Sanjay Kumar Summary Actomyosin stress fibers (SFs) enable cells to exert traction on planar extracellular matrices (ECMs) by tensing focal adhesions (FAs) at the cell–ECM interface. Although it is widely appreciated that the spatial and temporal distribution of these tensile...
Includes: Supplementary data
Journal Articles
Journal Articles
J Cell Sci (2012) 125 (8): 1855–1864.
Published: 15 April 2012
...Sari Tojkander; Gergana Gateva; Pekka Lappalainen Actin filaments assemble into diverse protrusive and contractile structures to provide force for a number of vital cellular processes. Stress fibers are contractile actomyosin bundles found in many cultured non-muscle cells, where they have...
Journal Articles
Journal Articles
J Cell Sci (2007) 120 (22): 3989–3998.
Published: 15 November 2007
... factors Lsc/p115 RhoGEF and LARG are activated when cells are plated onto fibronectin, but not other exchange factors such as Ect2 or Dbl. Knockdown of Lsc and LARG together significantly decreases RhoA activation and formation of stress fibers and focal adhesions downstream of fibronectin adhesion...
Journal Articles
J Cell Sci (2007) 120 (9): 1654–1662.
Published: 1 May 2007
... by the P2Y 2 R agonist UTP but completely inhibited activation of G 12 and G 12 -mediated events, including Rho activation, cofilin and myosin light chain-2 phosphorylation, stress fiber formation and chemotaxis towards UTP. The involvement of G 12 in all these events was verified by using a dominant...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2006) 119 (16): 3316–3324.
Published: 15 August 2006
... and adhesion, including stress fibers, focal adhesions, cell-cell junctions, growth cones and Z-discs. Here, we show that palladin also localizes to the dorsal, circular ruffles that form transiently in response to growth factor stimulation. More importantly, palladin knockdown results in decreased ruffle...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2003) 116 (23): 4777–4790.
Published: 1 December 2003
... in vitro and in vivo, and that this phosphorylation occurs preferentially at residue Ser19. In quiescent fibroblasts, DAP kinase stabilizes stress fibers through phosphorylation of MLC, but it is dispensable for the formation of peripheral microfilament bundles. This cytoskeletal effect of DAP kinase...
Journal Articles
J Cell Sci (2003) 116 (9): 1745–1755.
Published: 1 May 2003
... truncation mutant (ΔC, residues 1-1010),which lacks an autoinhibitory protein-protein interaction domain, displayed prominent stress fibers. FHOD1 (1-421) did not induce stress fibers but localized to membrane ruffles in a manner similar to the full-length protein,indicating that the FH1 and FH2 domains...
Journal Articles
Journal Articles
J Cell Sci (2001) 114 (18): 3285–3296.
Published: 15 September 2001
...-A fibronectin exerts a permissive action for α-smooth muscle actin expression. A morphological continuity (called fibronexus), a specialized form of focal adhesion, has been described between actin stress fibers that contain α-smooth muscle actin, and extracellular fibronectin, which contains the ED-A portion...
Journal Articles
Journal Articles