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Keywords: Stem cell
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Journal Articles
J Cell Sci (2024) 137 (5): jcs261789.
Published: 11 March 2024
...Rhiannon R. Penkert; Bryce LaFoya; Lucille Moholt-Siebert; Elizabeth Vargas; Sarah E. Welch; Kenneth E. Prehoda ABSTRACT Drosophila neural stem cells, or neuroblasts, rapidly proliferate during embryonic and larval development to populate the central nervous system. Neuroblasts divide...
Includes: Supplementary data
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In collection:
Stem cells
J Cell Sci (2024) 137 (4): jcs261482.
Published: 28 February 2024
...Tanja Müller; Marina Reichlmeir; Ann-Christin Hau; Ilka Wittig; Dorothea Schulte ABSTRACT Tight control over transcription factor activity is necessary for a sensible balance between cellular proliferation and differentiation in the embryo and during tissue homeostasis by adult stem cells...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2022) 135 (14): jcs260249.
Published: 19 July 2022
... comprise heterogeneous populations of stem and differentiated cells. Here, we examine Ca 2+ dynamics in the adult Drosophila intestine, a self-renewing epithelial organ in which stem cells continuously produce daughters that differentiate into either enteroendocrine cells or enterocytes. Live imaging...
Includes: Supplementary data
Journal Articles
In collection:
Autophagy
J Cell Sci (2021) 134 (5): jcs252973.
Published: 25 November 2020
... of xenophagy in macrophages targets Mtb to autophagosomes; however, how Mtb is targeted to autophagosomes in human macrophages at a high spatial and temporal resolution is unknown. Here, we use human induced pluripotent stem cell-derived macrophages (iPSDMs) to study the human macrophage response to Mtb...
Includes: Supplementary data
Journal Articles
In collection:
Stem cells
J Cell Sci (2020) 133 (8): jcs237545.
Published: 24 April 2020
...Annelies Wouters; Jan-Pieter Ploem; Sabine A. S. Langie; Tom Artois; Aziz Aboobaker; Karen Smeets ABSTRACT Pluripotent stem cells hold great potential for regenerative medicine. Increased replication and division, such is the case during regeneration, concomitantly increases the risk of adverse...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (8): jcs237545.
Published: 24 April 2020
...Annelies Wouters; Jan-Pieter Ploem; Sabine A. S. Langie; Tom Artois; Aziz Aboobaker; Karen Smeets ABSTRACT Pluripotent stem cells hold great potential for regenerative medicine. Increased replication and division, such is the case during regeneration, concomitantly increases the risk of adverse...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (8): jcs228551.
Published: 26 April 2019
... between Auxin and Cytokinin specifies vascular pattern in roots . Curr. Biol.   21 , 917 - 926 . 10.1016/j.cub.2011.04.017 Bringmann , M. and Bergmann , D. C. ( 2017 ). Tissue-wide mechanical forces influence the polarity of stomatal stem cells in Arabidopsis . Curr. Biol.   27...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (8): jcs228551.
Published: 26 April 2019
... signaling and polarity proteins. Arabidopsis Asymmetric cell division SPEECHLESS Cell–cell signaling Stem cell Stomata National Institutes of Health 10.13039/100000002 NIH5T32GM007276 Howard Hughes Medical Institute 10.13039/100000011 Stomata are pores...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (2): jcs208215.
Published: 29 January 2018
... complex that comprises ERF and transcription factors of the GRAS domain type. This interaction turns ERFs into highly potent and stress-responsive activators of cell proliferation. The potency to induce stem cell identity suggests that these heterodimeric transcription factor complexes could become...
Journal Articles
Journal Articles
J Cell Sci (2018) 131 (2): jcs208215.
Published: 29 January 2018
... complex that comprises ERF and transcription factors of the GRAS domain type. This interaction turns ERFs into highly potent and stress-responsive activators of cell proliferation. The potency to induce stem cell identity suggests that these heterodimeric transcription factor complexes could become...
Journal Articles
Journal Articles
J Cell Sci (2015) 128 (6): 1230–1240.
Published: 15 March 2015
...-long actin-rich filopodia, termed cytonemes, provides one mechanism for this spatiotemporal regulation of extracellular cues. We provide here a mechanism whereby the stem-cell marker Lgr5, and its family member Lgr4, promote the formation of cytonemes. Lgr4- and Lgr5-induced cytonemes exceed lengths...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5261–5272.
Published: 15 December 2014
...Takashi Nakamura; Yasuo Yoshitomi; Kiyoshi Sakai; Vyomesh Patel; Satoshi Fukumoto; Yoshihiko Yamada ABSTRACT The basal layer of the epidermis contains stem cells and transit amplifying cells that rapidly proliferate and differentiate further into the upper layers of the epidermis. A number...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (18): 3885–3891.
Published: 15 September 2014
...Robert Y. L. Tsai ABSTRACT A quintessential trait of stem cells is embedded in their ability to self-renew without incurring DNA damage as a result of genome replication. One key self-renewal factor is the nucleolar GTP-binding protein nucleostemin (also known as guanine-nucleotide-binding protein...
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J Cell Sci (2010) 123 (8): 1191–1201.
Published: 15 April 2010
... to cell within the brains of afflicted individuals, thereby spreading the specific neurodegenerative phenotypes distinctive to the protein being converted to amyloid. Importantly, this transmissibility mandates a re-evaluation of emerging neuronal graft and stem-cell therapies. In this Commentary, we...