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Keywords: Stem
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Journal Articles

Wnt/β-catenin mediates radiation resistance of Sca1 + progenitors in an immortalized mammary gland cell line

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Mercy S. Chen, Wendy A. Woodward, Fariba Behbod, Sirisha Peddibhotla, Maria P. Alfaro, Thomas A. Buchholz, Jeffrey M. Rosen
Journal: Journal of Cell Science
J Cell Sci (2007) 120 (3): 468–477.
https://doi.org/10.1242/jcs.03348
Published: 1 February 2007
... as a model, we sought to study the radioresistance of mammary progenitor cells. Using the putative progenitor cell marker stem cell antigen 1 (Sca1), we were able to isolate a discrete subpopulation of Sca1 + multipotent cells from the immortalized COMMA-Dβ-geo murine mammary cell line. At a clinically...
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Journal Articles

In vivo contribution of murine mesenchymal stem cells into multiple cell-types under minimal damage conditions

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Fernando Anjos-Afonso, Elena K. Siapati, Dominique Bonnet
Journal: Journal of Cell Science
J Cell Sci (2004) 117 (23): 5655–5664.
https://doi.org/10.1242/jcs.01488
Published: 1 November 2004
...Fernando Anjos-Afonso; Elena K. Siapati; Dominique Bonnet Murine mesenchymal stem cells are capable of differentiating in vitro into different lineages under stimulation with certain cytokines, growth factors and chemicals. However, the true capacitiy of these cells to contribute to different cell...
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Journal Articles

Isolation of human progenitor liver epithelial cells with extensive replication capacity and differentiation into mature hepatocytes

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Harmeet Malhi, Adil N. Irani, Singh Gagandeep, Sanjeev Gupta
Journal: Journal of Cell Science
J Cell Sci (2002) 115 (13): 2679–2688.
https://doi.org/10.1242/jcs.115.13.2679
Published: 1 July 2002
...Harmeet Malhi; Adil N. Irani; Singh Gagandeep; Sanjeev Gupta The liver can regenerate itself through the progenitor cells it harbors. Here we demonstrate isolation of epithelial progenitor/stem cells from the fetal human liver, which contains a large number of hepatoblasts. Progenitor liver cells...
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