... attributed. Summary: HDLs, akin to their capacity for extracting cholesterol, can remove lipophilic compounds from cells, thus protecting the cells when these compounds are toxic. High-density lipoprotein HDL Cell death Thapsigargin Glibenclamide Staurosporine Doxorubicin Rhodamine 123...

...A. Pedro Gonçalves; J. Miguel Cordeiro; João Monteiro; Alberto Muñoz; Paulo Correia-de-Sá; Nick D. Read; Arnaldo Videira ABSTRACT The model organism Neurospora crassa undergoes programmed cell death when exposed to staurosporine. Here, we show that staurosporine causes defined changes in cytosolic...

... stopped by adding SDS sample buffer and boiling, then analyzed by SDS PAGE followed by autoradiography, or Coomassie Blue staining to stain for total histone H1. Cells expressing 3HA tagged cyclin B were untreated, treated with 1 µM calyculin A or 0.2 µM staurosporine as indicated, then lysed under...

...: Department of Respiratory Medicine, Changhai Hospital, Second Military Medical University, Shanghai 200433, People's Republic of China 5 6 2008 © The Company of Biologists Limited 2008 2008 Cyclase-associated protein Srv2 ASP-56 Reactive oxygen species Cytochrome c Staurosporine...

... in millimolar concentrations. ‘Kiss-and-run’ type of release is enhanced by the kinase inhibitor staurosporine, which suggests that this secretion mode is regulated by protein phosphorylation. We also observed capacitance bursts, which most probably represent ‘hot spots’ of secretion and we found that ‘kiss...

...). In these neurons, apoptosis can be induced by the withdrawal of nerve growth factor (NGF) and also by the addition of the kinase inhibitor staurosporine. p35 has been shown to be a broad spectrum inhibitor of the caspase family and promotes the survival of SCG neurons withdrawn from NGF. We show that p35 is also...

... with staurosporine, a protein kinase alkaloid inhibitor, induced an elevation of tau protein levels and outgrowth of stable neurites. In this study, we analyzed the mechanism(s) by which nerve growth factor and staurosporine exert their effects on tau levels. We demonstrate that nerve growth factor affects tau mRNA...

... + gene does not. Involvement of n PKCs in cell wall formation and actin organization was also clarified. The effect of staurosporine (a potent inhibitor of protein kinases) on regenerating protoplasts of the three strains confirmed the assumption that the pck2 protein is an in vivo target...