...-immunoprecipitate with c-Src ( Roy et al., 2020 ), suggesting formation of transbilayer-spanning complexes. Indeed, various Src-family kinases are associated with flotillins and flotillin nanodomains ( Stuermer, 2010 ). Furthermore, c-Src directly binds to the HER2 kinase domain ( Kim et al., 2005 ; Marcotte et al...

... CD36 exists in nanoclusters enriched with the downstream effector Fyn when unligated; multivalent ligands enhance the clusters and activate Fyn, bypassing de novo recruitment of Fyn to the clusters. CD36 Receptor and membrane biology Signal transduction Src-family kinase Super-resolution...

... formation and actin stress fibre assembly. We have identified ARAP3 as a phosphorylated target of protein tyrosine kinases. In cells, ARAP3 was tyrosine phosphorylated when co-expressed with Src-family kinases (SFKs), upon stimulation with growth factors and during adhesion to the extracellular matrix (ECM...