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Keywords: Sphingolipid
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Journal Articles
J Cell Sci (2015) 128 (19): 3646–3659.
Published: 01 October 2015
... that several growth phenotypes linked to PMP3 deletion can be modulated by the removal of specific genes involved in sphingolipid synthesis. These genetic interactions, together with lipid binding assays and epifluorescence microscopy, as well as other biochemical experiments, suggest that Pmp3p could be part...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (14): 2454–2467.
Published: 15 July 2015
... clustering remain poorly understood. In this study, we demonstrate a role for sphingolipids in telomere clustering in the budding yeast Saccharomyces cerevisiae . Because abnormal sphingolipid metabolism causes downregulation of expression levels of genes involved in telomere organization, sphingolipids...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1578–1587.
Published: 01 May 2010
...Mai Nakase; Motohiro Tani; Tomotake Morita; Hiroko K. Kitamoto; Jun Kashiwazaki; Taro Nakamura; Akira Hosomi; Naotaka Tanaka; Kaoru Takegawa In Saccharomyces cerevisiae , three classes of sphingolipids contain myo -inositol – inositol phosphorylceramide (IPC), mannosylinositol phosphorylceramide...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (20): 3715–3728.
Published: 15 October 2009
...Dawei Zhang; Manoj Manna; Thorsten Wohland; Rachel Kraut Several cholesterol-dependent cellular uptake pathways involving microdomain-resident sphingolipids have been characterized, but little is known about what controls the further intracellular trafficking routes of those domains. Here, we...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (4): 443–452.
Published: 15 February 2009
... of the model. The two major classes of lipids within the Golgi are glycerophospholipids (GPLs) and sphingolipids (SLs), and their trafficking routes differ significantly. GPL synthesis takes place in the ER and forward secretory transport carries these lipids to the Golgi. GPL transport is expressed as the sum...