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Keywords: Spermatogenesis
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Journal Articles
J Cell Sci jcs.259036.
Published: 21 December 2021
... spermatogenesis. * Authors for correspondence: xinwu@njmu.edu.cn ; wangmei@njmu.edu.cn 17 6 2021 14 12 2021 © 2021. Published by The Company of Biologists Ltd 2021 http://www.biologists.com/user-licence-1-1/ DNA/RNA-binding protein (DRBP) Male fertility...
Journal Articles
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Stem Cells
J Cell Sci (2021) 134 (14): jcs258757.
Published: 22 July 2021
... regulator of dedifferentiation from spermatogonia to germline stem cells in the Drosophila testis via its ability to downregulate nos expression. Dedifferentiation Spermatogenesis Drosophila Germ cells Howard Hughes Medical Institute http://dx.doi.org/10.13039/100000011...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (14): jcs235937.
Published: 16 July 2020
.... Less is known about the role of mitochondrial dynamics in developmental systems that involve changes in metabolic function. One such system is spermatogenesis. The first mitochondrial dynamics gene, Fuzzy onions ( Fzo ), was discovered in 1997 to mediate mitochondrial fusion during Drosophila...
Journal Articles
J Cell Sci (2019) 132 (14): jcs229849.
Published: 15 July 2019
... is to inhibit transcription factor E2F3. Without functional RB, E2F3 can drive adult Sertoli cells to resume proliferation. As a result, Sertoli cells are unable to support the spermatogonial stem cell niche, spermatogenesis and blood–testis barrier integrity, which ultimately leads to infertility. This study...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (17): jcs217125.
Published: 03 September 2018
...So Maezawa; Kazuteru Hasegawa; Kris G. Alavattam; Mayuka Funakoshi; Taiga Sato; Artem Barski; Satoshi H. Namekawa ABSTRACT Spermatogenesis involves the progressive reorganization of heterochromatin. However, the mechanisms that underlie the dynamic remodeling of heterochromatin remain unknown. Here...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (17): 2854–2866.
Published: 01 September 2017
..., causes sterility in male mice. Here, we present a detailed investigation of the specific function of IP6K1 in spermatogenesis. Within the mouse testis, IP6K1 is expressed at high levels in late stage pachytene spermatocytes and in round spermatids. We found IP6K1 to be a novel component of the chromatoid...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (16): 2722–2735.
Published: 15 August 2017
...Sunghee Yoon; Ichiro Kawasaki; Yhong-Hee Shim ABSTRACT Depletion of cyb-1 , a major B-type cyclin expressed during Caenorhabditis elegans spermatogenesis, causes a meiotic division arrest in diakinesis-stage spermatocytes with multiple and mispositioned centrosomes. Association of the two nuclear...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (3): 492–501.
Published: 01 February 2016
... fertility, providing evidence for a link between Htt and spermatogenesis; however, the underlying mechanism remains unclear. To understand better the function of Htt in spermatogenesis, we restricted the genetic deletion specifically to the germ cells using the Cre/ loxP site-specific recombination strategy...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (10): 1969–1981.
Published: 15 May 2015
... or financial interests. 17 12 2014 18 3 2015 © 2015. Published by The Company of Biologists Ltd 2015 Drosophila melanogaster Telomere Capping protein Male germline Spermatogenesis Telomeres are specialized structures that organize the extremities of linear chromosomes...
Journal Articles
J Cell Sci (2014) 127 (22): 4870–4882.
Published: 15 November 2014
..., the BTB undergoes cyclic restructuring during spermatogenesis so that preleptotene spermatocytes are transported across the BTB at stage VII–VIII of the epithelial cycle to enter the apical compartment for maturation ( Cheng and Mruk, 2010 ; Cheng and Mruk, 2012 ; Smith and Braun, 2012 ). Although...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (10): 2174–2188.
Published: 15 May 2014
... and spermatogenesis. * These authors contributed equally to this work ‡ Author for correspondence ( sdalal@actrec.gov.in ) Competing interests The authors declare no competing interests. 18 12 2012 31 01 2014 © 2014. Published by The Company of Biologists Ltd 2014 14-3-3γ...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (17): 3927–3938.
Published: 01 September 2013
..., and the protein was found associated with the XY body. As complete loss of RAD9A is embryonic lethal, we constructed and characterized a mouse strain with Stra8-Cre driven germ cell-specific ablation of Rad9a beginning in undifferentiated spermatogonia in order to assess its role in spermatogenesis. Adult mutant...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (14): 3095–3104.
Published: 15 July 2013
...Emad A. Ahmed; Agnel Sfeir; Hiroyuki Takai; Harry Scherthan Summary Spermatogenesis is a complex process that generates haploid germ cells or spores and implements meiosis, a succession of two special cell divisions that are required for homologous chromosome segregation. During prophase...
Includes: Supplementary data
Journal Articles
J Cell Sci (2011) 124 (18): 3137–3148.
Published: 15 September 2011
... differentiation in the testis and for sustained spermatogenesis. * These authors contributed equally to this work ‡ Author for correspondence ( Andreas.Winterpacht@uk-erlangen.de ) 17 5 2011 © 2011. 2011 Spermatogonial stem cell Differentiation SPOC1 (PHF13) Spermatogenesis...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (16): 2763–2772.
Published: 15 August 2010
... spermatogenesis. Production of spag4 mRNA is limited to the testis, and Spag4 protein shows a dynamic pattern of association with the germline nuclei, including a concentration of protein at the site of attachment of the single spermatid centriole. In the absence of Spag4, nuclei and centrioles or basal bodies...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (6): 871–880.
Published: 15 March 2010
..., retinoic acid, regulate meiotic initiation in both spermatogenesis and oogenesis in mice . Proc. Natl. Acad. Sci. USA 105 , 14976 - 14980 . Beck A. R. , Miller I. J. , Anderson P. , Streuli M. ( 1998 ). RNA-binding protein TIAR is essential for primordial germ cell...
Journal Articles
J Cell Sci (2010) 123 (3): 331–339.
Published: 01 February 2010
... to haploid gene expression, in mammalian round spermatids. However, little is known about functions and fate of the CB at later steps of spermatogenesis, when elongating spermatids undergo chromatin compaction and transcriptional silencing. In mouse elongating spermatids, we detected accumulation...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (16): 2866–2876.
Published: 15 August 2009
... of constitutive secretion at lower temperature. Our findings point to an essential role of FetA in Golgi morphology and secretory function, suggesting a crucial role for this novel murine P4-ATPase in spermatogenesis. § Authors for correspondence ( xyding@sunm.shcnc.ac.cn ; tgp@life.ku.dk...
Journal Articles
J Cell Sci (2009) 122 (15): 2686–2698.
Published: 01 August 2009
... of Biologists Limited 2009 2009 Chromosome segregation Cohesin Meiosis Oocyte maturation Separase Spermatogenesis Sister chromatid cohesion is mediated by a multi-subunit complex called cohesin ( Nasmyth, 2005 ). During mitosis, cohesin resists the tendency of microtubules to pull sister...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (10): 1529–1539.
Published: 15 May 2009
...Melissa A. Henderson; Elizabeth Cronland; Steve Dunkelbarger; Vince Contreras; Susan Strome; Brett D. Keiper Fertility and embryonic viability are measures of efficient germ cell growth and development. During oogenesis and spermatogenesis, new proteins are required for both mitotic expansion...