...Géraldine Laloux; Christine Jacobs-Wagner ABSTRACT It is now well appreciated that bacterial cells are highly organized, which is far from the initial concept that they are merely bags of randomly distributed macromolecules and chemicals. Central to their spatial organization is the precise...

... is likely to generate high concentrations of IP 3 that flood the cytosol and obscure spatial organization. HEK cells provide the experimental convenience of working with all M 3 R activated while retaining physiologically relevant spatial organization. This experimental opportunity allowed us...

... intranuclear structures. Altogether, our data suggest a mechanical link between changes in lamina spatial organization and the formation of telomere aggregates during senescence of hMSCs, which can possibly contribute to changes in nuclear activity during cell senescence. * Author for correspondence (e...