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Keywords: Sorting nexin
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Autophagy
J Cell Sci (2020) 133 (14): jcs246306.
Published: 15 July 2020
...Zuriñe Antón; Virginie M. S. Betin; Boris Simonetti; Colin J. Traer; Naomi Attar; Peter J. Cullen; Jon D. Lane ABSTRACT The sorting nexins (SNXs) are a family of peripheral membrane proteins that direct protein trafficking decisions within the endocytic network. Emerging evidence in yeast...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (17): jcs211672.
Published: 10 September 2018
...Chris M. Danson; Neil Pearson; Kate J. Heesom; Peter J. Cullen ABSTRACT The endo-lysosomal network serves an essential role in determining the fate of endocytosed transmembrane proteins and their associated proteins and lipids. Sorting nexins (SNXs) play a central role in the functional...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (2): jcs203695.
Published: 29 January 2018
... of cargo proteins, mediated by the retromer complex. Recent work has led to significant progress in understanding the role of Arabidopsis retromer subunits in recycling vacuolar sorting receptors and plasma membrane proteins. As a consequence, members of the sorting nexin (SNX) protein family...
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J Cell Sci (2015) 128 (9): 1848–1861.
Published: 1 May 2015
... 13 3 2015 © 2015. Published by The Company of Biologists Ltd 2015 SNX14 G protein‐coupled receptor Regulator of G protein signaling Sorting nexin Guanosine triphosphatase‐activating proteins 5‐hydroxytryptamine type 6 receptor 5‐HT G‐protein‐coupled receptors (GPCRs...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (3): 553–565.
Published: 1 February 2015
...Rajesh Ghai; Maria Tello-Lafoz; Suzanne J. Norwood; Zhe Yang; Thomas Clairfeuille; Rohan D. Teasdale; Isabel Mérida; Brett M. Collins ABSTRACT Sorting nexin 27 (SNX27) controls the endosomal-to-cell-surface recycling of diverse transmembrane protein cargos. Crucial to this function...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (22): 4940–4953.
Published: 15 November 2014
... Retromer Sorting nexin On arriving in the endosomal network, internalized transmembrane protein cargos have two principal fates – either they are sorted from the limiting membrane of the endosome into intraluminal vesicles for delivery to the lysosome for degradation or, alternatively...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (21): 4885–4899.
Published: 1 November 2013
...Chris Danson; Edward Brown; Oliver J. Hemmings; Ian J. McGough; Sam Yarwood; Kate J. Heesom; Jeremy G. Carlton; Juan Martin-Serrano; Margaret T. May; Paul Verkade; Peter J. Cullen Summary Sorting nexins (SNXs) are key regulators of the endosomal network. In designing an RNAi-mediated loss...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (21): 4963–4973.
Published: 1 November 2013
... . Hettema   E. H. , Lewis   M. J. , Black   M. W. , Pelham   H. R. ( 2003 ). Retromer and the sorting nexins Snx4/41/42 mediate distinct retrieval pathways from yeast endosomes.   EMBO J.   22 , 548 – 557 . 10.1093/emboj/cdg062 Huang   J. , Birmingham   C. L. , Shahnazari   S...
Includes: Supplementary data
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Journal Articles
J Cell Sci (2007) 120 (10): 1818–1828.
Published: 15 May 2007
... macropinocytosis of the E-cadherin-catenin complex into endosomal compartments that colocalized with EEA1 and the sorting nexin, SNX1. Depletion of cellular SNX1 levels by siRNA resulted in increased intracellular accumulation and turnover of E-cadherin internalized from the cell surface in response to EGF...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2007) 120 (1): 45–54.
Published: 1 January 2007
... is composed of two subcomplexes, one containing SNX1 and forming a membrane-bound coat, the other comprising VPS26, VPS29 and VPS35 and being cargo-selective. In yeast, an additional sorting nexin - Vps17p - is a component of the membrane bound coat. It remains unclear whether the mammalian retromer requires...
Includes: Multimedia, Supplementary data
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