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Keywords: Sortilin
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Journal Articles
J Cell Sci (2020) 133 (6): jcs234047.
Published: 16 March 2020
..., identifying a possible pathogenic mechanism to Batten disease. Endosomes CLN3 Retromer Sortilin Juvenile neuronal ceroid lipofuscinosis Rab7A EU Canadian Institutes for Health Research ENG-387575 Canadian Foundation for Innovation 35258 National...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (20): 3832–3844.
Published: 15 October 2016
.... The Shh full-length protein undergoes autocleavage in the endoplasmic reticulum to generate the biologically active N-terminal fragment (ShhN), which is destined for secretion. We identified sortilin (Sort1), a member of the VPS10P-domain receptor family, as a new Shh trafficking receptor. We demonstrate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (18): 3983–3997.
Published: 15 September 2014
... to the multifaceted receptor sortilin (also called neurotensin receptor 3). Sortilin is already known to be important for cancer cell function. Here, we report for the first time its role in the assembly of a tyrosine kinase complex and subsequent exosome release. This new complex (termed the TES complex) is found...
Includes: Supplementary data
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J Cell Sci (2014) 127 (16): 3477–3487.
Published: 15 August 2014
...Jennifer Baltes; Jakob Vejby Larsen; Karthikeyan Radhakrishnan; Constanze Geumann; Manuel Kratzke; Claus Munck Petersen; Peter Schu ABSTRACT Here, we describe altered sorting of sortilin in adipocytes deficient for the σ1B-containing AP-1 complex, leading to the inhibition of adipogenesis. The AP-1...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (14): 2502–2511.
Published: 15 July 2010
...Anna Wähe; Bahram Kasmapour; Christoph Schmaderer; David Liebl; Konrad Sandhoff; Anders Nykjaer; Gareth Griffiths; Maximiliano G. Gutierrez Sortilin, also known as neurotensin receptor 3 (NTR3), is a transmembrane protein with a dual function. It acts as a receptor for neuromediators and growth...
Includes: Multimedia, Supplementary data