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Effect of the distribution and clustering of the type I A BMP receptor(ALK3) with the type II BMP receptor on the activation of signalling pathways

Anja Nohe, Eleonora Keating, T. Michael Underhill, Petra Knaus, Nils O. Petersen

J Cell Sci (2003) 116 (16): 3277–3284.

https://doi.org/10.1242/jcs.00519

Published: 15 August 2003

... of the BRII and a constitutive active BRIa-ca is necessary for the activation of the Smad pathway. Importantly using a kinase-inactive BRII the rearrangement of BRIa is blocked. Together, these findings suggest that rearrangement of the receptors at the cell surface prior to forming preformed ligand...

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Effect of the distribution and clustering of the type I A BMP receptor(ALK3) with the type II BMP receptor on the activation of signalling pathways

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Effect of the distribution and clustering of the type I A BMP receptor(ALK3) with the type II BMP receptor on the activation of signalling pathways

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