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Keywords: Smad pathwayClose
Journal: Journal of Cell Science
J Cell Sci (2003) 116 (16): 3277–3284.
Published: 15 August 2003
... of the BRII and a constitutive active BRIa-ca is necessary for the activation of the Smad pathway. Importantly using a kinase-inactive BRII the rearrangement of BRIa is blocked. Together, these findings suggest that rearrangement of the receptors at the cell surface prior to forming preformed ligand...