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Keywords: Skeletal muscle
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Journal Articles
In collection:
Stem Cells
J Cell Sci (2022) 135 (4): jcs256008.
Published: 21 February 2022
... t -test. Since TLE family proteins play essential roles in cell fate specification and differentiation, we explored whether TLEs are expressed in the skeletal muscle. We found that TLE4 is expressed in the adult mouse skeletal muscle; TLE4 is co-expressed in the satellite cells labeled...
Includes: Supplementary data
Journal Articles
J Cell Sci (2022) 135 (2): jcs259185.
Published: 25 January 2022
... in skeletal muscle. Sarcoplasmic reticulum Excitation-contraction coupling KEKE Skeletal muscle Triads Fondazione Telethon http://dx.doi.org/10.13039/501100002426 GGP19291 Ministry of Education, University and Research http://dx.doi.org/10.13039/501100003407 2015ZZR4W3...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2021) 134 (14): jcs256388.
Published: 23 July 2021
...Helena Pinheiro; Mafalda Ramos Pimentel; Catarina Sequeira; Luís Manuel Oliveira; Anna Pezzarossa; William Roman; Edgar R. Gomes ABSTRACT Skeletal muscle myofibers are large and elongated cells with multiple and evenly distributed nuclei. Nuclear distribution suggests that each nucleus influences...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (15): jcs243162.
Published: 11 August 2020
...-206 deletion shifts slow muscles to a faster profile and results in cardiac dysfunction specifically in male mice. miR-206 miRNA Skeletal muscle Heart Sexual dimorphism Skeletal muscle is a highly organized contractile tissue that comprises 40% of human body mass ( Janssen et al...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (19): jcs232157.
Published: 9 October 2019
...Osvaldo Contreras; Meilyn Cruz-Soca; Marine Theret; Hesham Soliman; Lin Wei Tung; Elena Groppa; Fabio M. Rossi; Enrique Brandan ABSTRACT Fibro–adipogenic progenitors (FAPs) are tissue-resident mesenchymal stromal cells (MSCs) required for proper skeletal muscle development, regeneration...
Includes: Supplementary data
Journal Articles
In collection:
Stem Cells
J Cell Sci (2019) 132 (13): jcs225946.
Published: 5 July 2019
.... Zammit; Henning Wackerhage ABSTRACT VGLL proteins are transcriptional co-factors that bind TEAD family transcription factors to regulate events ranging from wing development in fly, to muscle fibre composition and immune function in mice. Here, we characterise Vgll3 in skeletal muscle. We found...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (5): jcs223008.
Published: 4 March 2019
... aging, immunodeficiency, cancer predisposition, growth retardation and motor defects, but not cerebellar neurodegeneration and ataxia. We explored whether Atm loss is responsible for skeletal muscle defects by investigating myofiber morphology, oxidative/glycolytic activity, myocyte ultrastructural...
Journal Articles
In collection:
Mitochondria
J Cell Sci (2018) 131 (23): jcs221028.
Published: 5 December 2018
... the frequency of elongated mitochondrial constrictions, providing novel structural evidence for mitochondrial dynamics stages in mouse fast-twitch muscle fibers. Fatigue Fission Mitochondria Skeletal muscle * Author for correspondence ( manuelalavorato@gmail.com ) Competing interests...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (20): 3816–3831.
Published: 15 October 2016
...Paul Knopp; Yvonne D. Krom; Christopher R. S. Banerji; Maryna Panamarova; Louise A. Moyle; Bianca den Hamer; Silvère M. van der Maarel; Peter S. Zammit ABSTRACT Skeletal muscle wasting in facioscapulohumeral muscular dystrophy (FSHD) results in substantial morbidity. On a disease-permissive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (19): 3525–3531.
Published: 1 October 2015
... Summary: Collagen VI is a remarkable component of the extracellular matrix, and studies have highlighted a crucial role for this protein in a wide range of tissues under physiological and pathological conditions. Collagen Extracellular matrix Skeletal muscle Collagen VI (ColVI...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (2): 239–250.
Published: 15 January 2015
... muscle thin filament assembly. Furthermore, these studies demonstrate the value of Xenopus for the analysis of contractile protein function during de novo myofibril assembly. Relatively little is known concerning the precise roles of Tmod4 and Lmod3 during skeletal muscle development. To address...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5204–5217.
Published: 15 December 2014
... synthase (Invitrogen). Proteasome activity was assessed using Proteasome-Glo TM Assay kit (Promega) following the manufacturer's instruction. The trypsin-like and chymotrypsin-like activity assays were conducted using skeletal muscle homogenates in a total volume of 100 µl in opaque 96-well plates...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5157–5163.
Published: 15 December 2014
...Laura Collard; Gaëlle Herledan; Alessandra Pincini; Aline Guerci; Voahangy Randrianarison-Huetz; Athanassia Sotiropoulos ABSTRACT Skeletal muscle atrophy is a debilitating process that is associated with a wide variety of conditions including inactivity, disease and aging. Here, we demonstrate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (21): 4543–4548.
Published: 1 November 2014
...Yu Xin Wang; Nicolas A. Dumont; Michael A. Rudnicki ABSTRACT Muscle stem cells facilitate the long-term regenerative capacity of skeletal muscle. This self-renewing population of satellite cells has only recently been defined through genetic and transplantation experiments. Although muscle stem...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (21): 4589–4601.
Published: 1 November 2014
... membrane integrity and regulates signalling molecules during muscle hypertrophy. Satellite cells are resident myogenic progenitors in postnatal skeletal muscle that are involved in muscle growth and regenerative capacity. Postnatal muscle growth and satellite cell self-renewal require the transcription...
Includes: Supplementary data
Journal Articles
In collection:
Metabolism
J Cell Sci (2014) 127 (9): 1911–1923.
Published: 1 May 2014
... to insulin-stimulated glucose transport are unknown. We tested the impact of H 2 O 2 on insulin-dependent glucose transport and GLUT4 translocation in skeletal muscle cells. H 2 O 2 increased the translocation of GLUT4 with an exofacial Myc-epitope tag between the first and second transmembrane domains...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (3): 599–608.
Published: 1 February 2014
... previous studies have demonstrated that Sharp-1 is a negative regulator of skeletal myogenesis and it blocks differentiation of muscle precursor cells by modulating the activity of MyoD. In order to understand its role in pre- and post-natal myogenesis, we assessed skeletal muscle development and freeze...
Journal Articles
J Cell Sci (2013) 126 (24): 5610–5625.
Published: 15 December 2013
...Chibeza C. Agley; Anthea M. Rowlerson; Cristiana P. Velloso; Norman R. Lazarus; Stephen D. R. Harridge Summary We characterised the adherent cell types isolated from human skeletal muscle by enzymatic digestion, and demonstrated that even at 72 hours after isolation these cultures consisted...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (23): 5477–5489.
Published: 1 December 2013
...) generation and characterization of a novel knockin mouse model with a premature stop codon in the nebulin gene, eliminating its C-terminal SH3 domain (NebΔSH3 mouse). Surprisingly, detailed analyses of NebΔSH3 mice revealed no structural or histological skeletal muscle abnormalities and no changes in gene...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (23): 5325–5333.
Published: 1 December 2013
... of dysfunctional organelles and protein aggregates, whereas the ubiquitin-proteasome is important for the quality control of proteins. Post-mitotic tissues, such as skeletal muscle, are particularly susceptible to aged or dysfunctional organelles and aggregation-prone proteins. Therefore, these degradation systems...