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Keywords: Skeletal muscle
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Journal Articles
J Cell Sci (2021) 134 (14): jcs256388.
Published: 23 July 2021
...Helena Pinheiro; Mafalda Ramos Pimentel; Catarina Sequeira; Luís Manuel Oliveira; Anna Pezzarossa; William Roman; Edgar R. Gomes ABSTRACT Skeletal muscle myofibers are large and elongated cells with multiple and evenly distributed nuclei. Nuclear distribution suggests that each nucleus influences...
Includes: Supplementary data
Journal Articles
J Cell Sci (2020) 133 (15): jcs243162.
Published: 11 August 2020
.... C. , Maass , A. , Bell , M. L. , Byrnes , W. C. and Leinwand , L. A. ( 2001 ). Cardiac and skeletal muscle adaptations to voluntary wheel running in the mouse . J. Appl. Physiol.   90 , 1900 - 1908 . 10.1152/jappl.2001.90.5.1900 Allen , D. L. , Bandstra , E. R...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (19): jcs232157.
Published: 09 October 2019
...Osvaldo Contreras; Meilyn Cruz-Soca; Marine Theret; Hesham Soliman; Lin Wei Tung; Elena Groppa; Fabio M. Rossi; Enrique Brandan ABSTRACT Fibro–adipogenic progenitors (FAPs) are tissue-resident mesenchymal stromal cells (MSCs) required for proper skeletal muscle development, regeneration...
Includes: Supplementary data
Journal Articles
In collection:
Stem Cells
J Cell Sci (2019) 132 (13): jcs225946.
Published: 05 July 2019
.... Zammit; Henning Wackerhage ABSTRACT VGLL proteins are transcriptional co-factors that bind TEAD family transcription factors to regulate events ranging from wing development in fly, to muscle fibre composition and immune function in mice. Here, we characterise Vgll3 in skeletal muscle. We found...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (5): jcs223008.
Published: 04 March 2019
... aging, immunodeficiency, cancer predisposition, growth retardation and motor defects, but not cerebellar neurodegeneration and ataxia. We explored whether Atm loss is responsible for skeletal muscle defects by investigating myofiber morphology, oxidative/glycolytic activity, myocyte ultrastructural...
Journal Articles
In collection:
Mitochondria
J Cell Sci (2018) 131 (23): jcs221028.
Published: 05 December 2018
... of elongated mitochondrial constrictions, providing novel structural evidence for mitochondrial dynamics stages in mouse fast-twitch muscle fibers. Fatigue Fission Mitochondria Skeletal muscle Mitochondria, the cells' permanent guests, are very dynamic and extremely sensitive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2016) 129 (20): 3816–3831.
Published: 15 October 2016
...Paul Knopp; Yvonne D. Krom; Christopher R. S. Banerji; Maryna Panamarova; Louise A. Moyle; Bianca den Hamer; Silvère M. van der Maarel; Peter S. Zammit ABSTRACT Skeletal muscle wasting in facioscapulohumeral muscular dystrophy (FSHD) results in substantial morbidity. On a disease-permissive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (19): 3525–3531.
Published: 01 October 2015
... Summary: Collagen VI is a remarkable component of the extracellular matrix, and studies have highlighted a crucial role for this protein in a wide range of tissues under physiological and pathological conditions. Collagen Extracellular matrix Skeletal muscle Collagen VI (ColVI...
Includes: Supplementary data
Journal Articles
J Cell Sci (2015) 128 (2): 239–250.
Published: 15 January 2015
.... These three vertebrate proteins exhibit distinct adult tissue distributions, with Lmod1 reported to be smooth-muscle-specific, whereas Lmod2 and Lmod3 are present in both cardiac and skeletal muscle ( Conley et al., 2001 ; Nanda and Miano, 2012 ). Antibody and overexpression studies indicate that Lmod2...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5204–5217.
Published: 15 December 2014
... unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed. Proteasome Autophagy Skeletal muscle Muscle atrophy The ubiquitin–proteasome and autophagy–lysosome pathways are the two major routes for protein and organelle clearance...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (24): 5157–5163.
Published: 15 December 2014
...Laura Collard; Gaëlle Herledan; Alessandra Pincini; Aline Guerci; Voahangy Randrianarison-Huetz; Athanassia Sotiropoulos ABSTRACT Skeletal muscle atrophy is a debilitating process that is associated with a wide variety of conditions including inactivity, disease and aging. Here, we demonstrate...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (21): 4543–4548.
Published: 01 November 2014
...Yu Xin Wang; Nicolas A. Dumont; Michael A. Rudnicki ABSTRACT Muscle stem cells facilitate the long-term regenerative capacity of skeletal muscle. This self-renewing population of satellite cells has only recently been defined through genetic and transplantation experiments. Although muscle stem...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (21): 4589–4601.
Published: 01 November 2014
... by The Company of Biologists Ltd 2014 Desmin Muscle hypertrophy Intermediate filament Skeletal muscle Intermediate filaments (IFs) are filamentous components of the cytoskeleton of 10-nm diameter that mechanically connect various structures of the cytoplasmic space ( Lazarides, 1980...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (9): 1911–1923.
Published: 01 May 2014
... to insulin-stimulated glucose transport are unknown. We tested the impact of H 2 O 2 on insulin-dependent glucose transport and GLUT4 translocation in skeletal muscle cells. H 2 O 2 increased the translocation of GLUT4 with an exofacial Myc-epitope tag between the first and second transmembrane domains...
Includes: Supplementary data
Journal Articles
J Cell Sci (2014) 127 (3): 599–608.
Published: 01 February 2014
... previous studies have demonstrated that Sharp-1 is a negative regulator of skeletal myogenesis and it blocks differentiation of muscle precursor cells by modulating the activity of MyoD. In order to understand its role in pre- and post-natal myogenesis, we assessed skeletal muscle development and freeze...
Journal Articles
J Cell Sci (2013) 126 (24): 5610–5625.
Published: 15 December 2013
...Chibeza C. Agley; Anthea M. Rowlerson; Cristiana P. Velloso; Norman R. Lazarus; Stephen D. R. Harridge Summary We characterised the adherent cell types isolated from human skeletal muscle by enzymatic digestion, and demonstrated that even at 72 hours after isolation these cultures consisted...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (23): 5325–5333.
Published: 01 December 2013
... of dysfunctional organelles and protein aggregates, whereas the ubiquitin-proteasome is important for the quality control of proteins. Post-mitotic tissues, such as skeletal muscle, are particularly susceptible to aged or dysfunctional organelles and aggregation-prone proteins. Therefore, these degradation systems...
Journal Articles
J Cell Sci (2013) 126 (23): 5477–5489.
Published: 01 December 2013
...) generation and characterization of a novel knockin mouse model with a premature stop codon in the nebulin gene, eliminating its C-terminal SH3 domain (NebΔSH3 mouse). Surprisingly, detailed analyses of NebΔSH3 mice revealed no structural or histological skeletal muscle abnormalities and no changes in gene...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (15): 3314–3323.
Published: 01 August 2013
...Katrin Domsch; Nader Ezzeddine; Hanh T. Nguyen Summary Organized sarcomeric striations are an evolutionarily conserved hallmark of functional skeletal muscles. Here, we demonstrate that the Drosophila Abba protein, a member of the TRIM/RBCC superfamily, has a pivotal regulatory role in maintaining...
Includes: Supplementary data
Journal Articles
J Cell Sci (2013) 126 (9): 2092–2101.
Published: 01 May 2013
... rates indicate dynamic interactions. Whereas the skeletal muscle β 1a isoform formed stable complexes with Ca V 1.1 and Ca V 1.2, the non-skeletal muscle β 2a and β 4b isoforms dynamically interacted with both α 1 subunits. Neither replacing the I–II loop of Ca V 1.1 with that of Ca V 2.1, nor deletions...
Includes: Supplementary data