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Keywords: Shox2
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Journal Articles
J Cell Sci (2012) 125 (24): 6071–6083.
Published: 15 December 2012
... of the paralogous gene Shox2 results in severe rhizomelia. In this study, we show that Col2a1-Cre -driven deletion of Shox2 in developing chondrocytes also results in shortening of the stylopodial skeleton (i.e. humerus, femur) and that this rhizomelia is due to precocious chondrocyte maturation and hypertrophy. We...
Includes: Supplementary data