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Keywords: Sex body
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Journal Articles
J Cell Sci (2015) 128 (12): 2314–2327.
Published: 15 June 2015
... and Y chromosomes, except at a short region of homology capable of synapsis, referred to as the pseudoautosomal region (PAR; Fig. 2 A, white arrow). Additionally, to investigate sex body integrity, we examined localization of H2AX, a histone variant whose phosphorylation (resulting in γH2AX...
Includes: Supplementary data
Journal Articles
J Cell Sci (2009) 122 (12): 2149–2159.
Published: 15 June 2009
... breaks. In these spermatocytes, some telomeres do not attach to the nuclear envelope, and sex chromosomes do not form a sex body. Our data demonstrate an unpredicted participation of CDK2 in the accurate pairing and recombination between homologues during mammalian meiosis. Adult male C57BL/6 mice...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (15): 3233–3245.
Published: 01 August 2005
... is still considered to be dispensable for sex-body formation in mouse spermatocytes. We provide conclusive evidence showing that functional SPO11, and consequently recombination and synapsis, are required for phosphorylation of H2AX in the X-Y chromatin and for sex-body formation in mouse spermatocytes. We...
Includes: Supplementary data
Journal Articles
J Cell Sci (2002) 115 (21): 4097–4105.
Published: 01 November 2002
... that MSCI and sex-body formation are unaltered in mice with targeted mutations of Xist that prevent somatic X inactivation suggests that somatic X-inactivation and MSCI occur by fundamentally different mechanisms. References Armstrong, S. J., Kirkham, A. J. and Hultén, M. A. ( 1994 ). XY chromosome...
Includes: Supplementary data
Journal Articles
J Cell Sci (2001) 114 (18): 3367–3375.
Published: 15 September 2001
... histone macroH2A1.2. Previous analyses of M31 and macroH2A1.2 localisation in mouse testis sections have indicated that both proteins are components of meiotic centromeric heterochromatin and of the sex body, the transcriptionally inactive domain of the X and Y chromosomes. This second observation has...