... in the cell-cycle regulation of the fMAPK pathway, time-lapse fluorescence microscopy was performed. Msb2p-GFP and Sho1p-GFP fusion proteins were examined in cells expressing the septin Cdc3p-mCherry, which shows a distinct pattern of localization throughout the cell cycle ( Kim et al., 1991 ; Lippincott et...

...Alexander Mela; Michelle Momany ABSTRACT Septins colocalize with membrane sterol-rich regions and facilitate recruitment of cell wall synthases during wall remodeling. We show that null mutants missing an Aspergillus nidulans core septin present in hexamers and octamers (Δ aspA cdc11 , Δ aspB cdc3...

... in the right intracellular places at the right time. While significant progress has been made in understanding the self-assembly of actin and microtubule networks, less is known about how they are patterned and regulated in a site-specific manner. In mammalian systems, septins are a large family of GTP-binding...

...Rania Ghossoub; Qicong Hu; Marion Failler; Marie-Christine Rouyez; Benjamin Spitzbarth; Serge Mostowy; Uwe Wolfrum; Sophie Saunier; Pascale Cossart; W. James Nelson; Alexandre Benmerah Summary Septins are a large, evolutionarily conserved family of GTPases that form hetero-oligomers and interact...

... terminus. Although its localization depends on septins, a conserved family of GTP-binding proteins, Bud4 is necessary for the stable inheritance of septin rings during cell division. Although some anillins interact directly with septins, we find that neither DUF1709 nor the PH domain is necessary...

...Chang-Run Li; Jie-Ying Au Yong; Yan-Ming Wang; Yue Wang Cyclin-dependent kinases (CDKs) regulate septin organization in a cell-cycle-dependent manner in yeast. However, the mechanism remains unclear. Here, we show that the Candida albicans CDK Cdc28 phosphorylates the Nim1-related kinase Gin4...

...Jennifer R. Larson; Lukasz Kozubowski; Kelly Tatchell Septin complexes at the bud neck in Saccharomyces cerevisiae serve as a scaffold for proteins involved in signaling, cell cycle control, and cell wall synthesis. Many of these bind asymmetrically, associating with either the mother- or daughter...

...Elias T. Spiliotis; W. James Nelson Septins are conserved GTP-binding proteins that associate with cellular membranes and the actin and microtubule cytoskeletons. They polymerize to form filamentous structures that act as diffusion barriers between different membrane domains and as molecular...

...Claudia S. Petit; Sapna Mehta; Rachel H. Roberts; Kathleen L. Gould The fission yeast Schizosaccharomyces pombe divides through constriction of an actomyosin-based contractile ring followed by formation and degradation of a medial septum. Formation of an organized septin ring is also important...

...Hsin-Pei Shih; Karen G. Hales; John R. Pringle; Mark Peifer The septins are a family of proteins involved in cytokinesis and other aspects of cell-cortex organization. In a two-hybrid screen designed to identify septin-interacting proteins in Drosophila , we isolated several genes, including...