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Keywords: Separase
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Journal Articles
Journal Articles
J Cell Sci (2012) 125 (23): 5758–5769.
Published: 1 December 2012
.... * Author for correspondence ( [email protected] ) 17 8 2012 © 2012. Published by The Company of Biologists Ltd 2012 Caenorhabditis elegans Rab GTPase Cortical granule exocytosis Separase Phosphoinositide signalling plays an important role in various aspects of cell motility...
Includes: Supplementary data
Journal Articles
J Cell Sci (2012) 125 (22): 5353–5368.
Published: 15 November 2012
... that premature disengagement results from untimely activation of the anaphase-promoting complex (APC/C), leading to securin degradation and release of active separase. Although APC/C activation during G2 arrest is dependent on polo-like kinase 1 (Plk1)-mediated degradation of the APC/C inhibitor, early mitotic...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2011) 124 (17): 2903–2913.
Published: 1 September 2011
...Christopher T. Richie; Joshua N. Bembenek; Barry Chestnut; Tokiko Furuta; Jill M. Schumacher; Matthew Wallenfang; Andy Golden Mutations in the Caenorhabditis elegans separase gene, sep-1 , are embryonic lethal. Newly fertilized mutant embryos have defects in polar body extrusion, fail to undergo...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2009) 122 (15): 2686–2698.
Published: 1 August 2009
...Nobuaki R. Kudo; Martin Anger; Antoine H. F. M. Peters; Olaf Stemmann; Hans-Christian Theussl; Wolfgang Helmhart; Hiromi Kudo; Christa Heyting; Kim Nasmyth Proteolytic activity of separase is required for chiasma resolution during meiosis I in mouse oocytes. Rec8, the meiosis-specific α-kleisin...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (4): 733–742.
Published: 15 February 2005
...Rahul Pandey; Stefan Heidmann; Christian F. Lehner Separase cleaves a subunit of the cohesin complex and thereby promotes sister chromatid separation during mitotic and meiotic divisions. Drosophila separase associates with regulatory subunits encoded by the pimples and three rows genes. Three rows...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2003) 116 (12): 2453–2460.
Published: 15 June 2003
...Oliver Leismann; Christian F. Lehner Sister chromatid separation during exit from mitosis requires separase. Securin inhibits separase during the cell cycle until metaphase when it is degraded by the anaphase-promoting complex/cyclosome (APC/C). In Drosophila , sister chromatid separation proceeds...