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Keywords: Semaphorin 3A
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Journal Articles

TrkA mediates retrograde semaphorin 3A signaling through plexin A4 to regulate dendritic branching

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Naoya Yamashita, Masayuki Yamane, Fumikazu Suto, Yoshio Goshima
Journal: Journal of Cell Science
J Cell Sci (2016) 129 (9): 1802–1814.
https://doi.org/10.1242/jcs.184580
Published: 1 May 2016
...Naoya Yamashita; Masayuki Yamane; Fumikazu Suto; Yoshio Goshima ABSTRACT Semaphorin 3A (Sema3A), a secretory semaphorin, exerts various biological actions through a complex between neuropilin-1 and plexin-As (PlexAs). Sema3A induces retrograde signaling, which is involved in regulating dendritic...
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Journal Articles

PTEN couples Sema3A signalling to growth cone collapse

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Neil H. Chadborn, Aminul I. Ahmed, Mark R. Holt, Rabinder Prinjha, Graham A. Dunn, Gareth E. Jones, Britta J. Eickholt
Journal: Journal of Cell Science
J Cell Sci (2006) 119 (5): 951–957.
https://doi.org/10.1242/jcs.02801
Published: 1 March 2006
..., and are required for neurotrophin-mediated axon elongation. In addition, we have previously shown a dependency on GSK-3 activation in the semaphorin 3A (Sema3A)-mediated growth-cone-collapse response of sensory neurons. Regulation of GSK-3 activity involves the intermediate signalling lipid phosphatidylinositol...
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