... of both transmitter classes, establishing a mechanism for scaling co-transmission. Synaptic transmission Secretory granules Tyrosine phosphatase Vesicular transport Neuropeptide vesicles Many synapses feature co-transmission with small-molecule transmitters that rapidly activate...

... and might therefore be associated with the secretory granules. The endoplasmic reticulum is predominantly basal, but thin extensions penetrate into the granular area and cytosolic Ca 2+ signals probably initiate at sites where endoplasmic reticulum elements and granules come close together. * Author...

... to membranes, and few direct binding partners have been identified. In yeast, Gea2p has been implicated in trafficking through the Golgi apparatus and in maintaining Golgi structure. A major function of the Golgi apparatus is the packaging of cargo into secretory granules or vesicles. This process occurs...

... Endothelial cells Lysosome-related organelles Secretory granules Eukaryotic cells are divided into membrane-bounded compartments or organelles specialised for different biological processes. There are two major advantages to this compartmentalization: the separation of mutually incompatible...

...Rüdiger Rudolf; Tanja Kögel; Sergei A. Kuznetsov; Thorsten Salm; Oliver Schlicker; Andrea Hellwig; John A. Hammer, III; Hans-Hermann Gerdes Neuroendocrine secretory granules, the storage organelles for neuropeptides and hormones, are formed at the trans-Golgi network, stored inside the cell...

... in vitro are sufficient to account for the release of lytic granules in the intact T cell. This model system should be valuable for studying the interactions of secretory granules with microtubules, and for identifying the regulatory factors involved. † Author for correspondence at Department...

...Shian-Jiun Shih; David L. Nelson ABSTRACT Paramecium tetraurelia has thousands of secretory granules (trichocysts), which release their protein contents by regulated exocytosis. The secretory proteins that fill the granule comprise the condensed trichocyst matrix (ctmx) , a paracrystalline...

...Ellen Holm Nielsen ABSTRACT A freezing-thawing method for rupturing mast cells has made it possible to show that each of the secretory granules is surrounded by a regular network of filaments forming a basket-like structure. The filaments attach to the membrane with hook-like structures...