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Keywords: Sec61β
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Journal Articles
J Cell Sci (2010) 123 (13): 2170–2178.
Published: 1 July 2010
.... To this end, we analysed the cytosolic binding partners of Sec61β, a well-defined substrate of TRC40, and identified Bat3 as a previously unknown interacting partner. Depletion of Bat3 inhibits the membrane integration of Sec61β, but not of a second, TRC40-independent, tail-anchored protein, cytochrome b5...
Includes: Supplementary data
Journal Articles
J Cell Sci (2010) 123 (9): 1522–1530.
Published: 1 May 2010
... insertion of TA proteins from recombinant Asna1/TA protein complexes and ER-derived membranes. Our data show that Asna1 can mediate membrane insertion of RAMP4 and Sec61β without the participation of other cytosolic proteins by a mechanism that depends on the presence of ATP or ADP and a protease-sensitive...
Includes: Supplementary data
Journal Articles
J Cell Sci (2008) 121 (11): 1832–1840.
Published: 1 June 2008
... for membrane insertion of three TA proteins, RAMP4, Sec61β and cytocrome b5. We show here that newly synthesised RAMP4 and Sec61β can accumulate in a cytosolic, soluble complex with the ATPase Asna1 before insertion into ER-derived membranes. Membrane insertion of these TA proteins is stimulated by ATP...
Includes: Supplementary data
Journal Articles