...Eva Sonnenberg-Riethmacher; Michaela Miehe; Dieter Riethmacher ABSTRACT Neuregulin ligands and their ErbB receptors are important for the development of Schwann cells, the glial cells of the peripheral nervous system (PNS). ErbB3 deficiency is characterized by a complete loss of Schwann cells along...

... affects the function of various tumor-cell types. Here, we demonstrate that CXCR7 is an active component of SDF-1 signalling in astrocytes and Schwann cells. Cultured cortical astrocytes and peripheral nerve Schwann cells exhibit comparable total and cell-surface levels of expression of both SDF-1...

... for merlin-mediated inhibition of primary Schwann cell proliferation. Furthermore, we demonstrate that the F1 subdomain of the merlin FERM domain is required for actin colocalization, proper regulation of merlin C-terminal phosphorylation and for remodeling the cytoskeleton, yet is not required...

... their molecular structure and binding partners have been characterized, the functional roles of the four matrilin family members in vivo are still largely unknown. Here, we show that matrilin 2, expressed in pre-myelinating Schwann cells during normal development, profoundly influences the behaviour of glial...

...In Sun Han; Tae Beom Seo; Kwan-Hoi Kim; Jin-Hwan Yoon; Sung-Jin Yoon; Uk Namgung Schwann cell migration facilitates peripheral nerve regeneration after injury. We have recently found increased activation of Cdc2 kinase in regenerating sciatic nerves. Here we show that Cdc2 phosphorylation...

... additional adhesive mechanisms. * Author for correspondence (e-mail: laflams@mail.amc.edu 23 5 2003 © The Company of Biologists Limited 2003 2003 Endothelial cells Integrins α6β4 Angiogenesis Development Explant cultures Schwann cells The vascular system...

...@makek.dstb.uniud.it ) 17 12 2002 © The Company of Biologists Limited 2003 2003 Tetraspan proteins Peripheral neuropathies Schwann cells Myelin PIP 2 Growth arrest specific 3 (Gas3)/peripheral myelin protein 22 (PMP22) is a glycoprotein highly expressed in Schwann cells (SCs), where...