... version of GLUT4 under the control of a muscle-specific promoter. The exofacial HA-tag has enabled fluorescent labelling of only the GLUT4 exposed at the external surface. A distinction between sarcolemma labelling and transverse-tubule labelling has also been possible because the former compartment...

... and to the sarcolemma in striated muscle. We examined the contractile properties and morphology of fast-twitch skeletal muscle from mice lacking keratin 19. Tibialis anterior muscles of keratin-19-null mice showed a small but significant decrease in mean fiber diameter and in the specific force of tetanic contraction...

...@umassmed.edu ) 11 2 2003 © The Company of Biologists Limited 2003 2003 Costamere Sarcolemma Membrane skeleton C2C12 cells 50MB-1 cells Organized complexes of membrane-associated cytoskeletal proteins (membrane skeletons) maintain the integrity and organization of the plasma...