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Keywords: Salivary gland
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Journal Articles
In collection:
Membrane trafficking
J Cell Sci (2023) 136 (6): jcs260366.
Published: 5 March 2023
.... Here, we identified the conserved actin-crosslinking protein Swip-1 as a novel regulator controlling exocytosis of glue granules in the Drosophila salivary gland. Real-time imaging revealed that Swip-1 is simultaneously recruited with F-actin onto secreting granules in proximity to the apical membrane...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2022) 135 (5): jcs259086.
Published: 20 August 2021
... sites in both yeast cells and the Drosophila larval salivary glands, and this localization is mediated by an N-terminal ER membrane anchor and conserved C-terminal sequences. The C-terminus of Hobbit binds to plasma membrane phosphatidylinositols, and the distribution of these lipids is altered...
Includes: Supplementary data
Journal Articles
Series: REVIEW COMMONS TRANSFER
J Cell Sci (2021) 134 (15): jcs259037.
Published: 3 August 2021
...); after budding from the TGN, granules undergo modifications, including an increase in size. These changes occur during a poorly understood process called secretory granule maturation. Here, we leverage the Drosophila larval salivary glands as a model to characterize a novel role for Rab GTPases during...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (9): 1559–1569.
Published: 1 May 2017
... culture Branching morphogenesis Fibroblast growth factor Macrophage colony-stimulating factor Neurturin Salivary gland During development, the submandibular gland (SMG) tissue undergoes unique morphological changes (termed branching morphogenesis) that share similarities with changes seen...
Includes: Supplementary data
Journal Articles
In collection:
Imaging
J Cell Sci (2017) 130 (8): 1355–1363.
Published: 15 April 2017
...Duy T. Tran; Kelly G. Ten Hagen ABSTRACT Real-time imaging of regulated exocytosis in secreting organs can provide unprecedented temporal and spatial detail. Here, we highlight recent advances in 3D time-lapse imaging in Drosophila salivary glands at single-granule resolution. Using fluorescently...
Includes: Supplementary data
Journal Articles
J Cell Sci (2006) 119 (16): 3376–3384.
Published: 15 August 2006
..., and investigated cell migration using two-color confocal time-lapse microscopy to image cell and extracellular-matrix dynamics in developing salivary glands. We labeled submandibular salivary gland (SMG) epithelial cells with green fluorescent protein and matrix with fluorescent fibronectin. Surprisingly, we...
Includes: Multimedia, Supplementary data
Journal Articles
J Cell Sci (2005) 118 (18): 4131–4139.
Published: 15 September 2005
...-mail: pt207@cam.ac.uk ) 9 6 2005 © The Company of Biologists Limited 2005 2005 Acinar Salivary gland Calcium Lumen The importance of intracellular Ca 2+ in stimulus-secretion coupling in secretory epithelial cells has been long recognized ( Matthews et al., 1973 ; Hunter et al...
Includes: Multimedia, Supplementary data
Journal Articles
Journal Articles
J Cell Sci (1996) 109 (8): 2013–2021.
Published: 1 August 1996
... immunofluorescence and immunoblot analysis for cystatin, a salivary gland acinar cell-specific protein found to be produced by differentiated HSG cells. Matrigel contains multiple extracellular matrix proteins, however, laminin-1 was identified as the major matrix component that induced HSG cell acinar development...
Journal Articles
Journal Articles
J Cell Sci (1995) 108 (4): 1407–1418.
Published: 1 April 1995
...Rebecca Kellum; Jordan W. Raff; Bruce M. Alberts ABSTRACT Heterochromatin protein 1 (HP1) was initially discovered as a protein that is associated with the heterochromatin at the chromocenter of polytene chromosomes in Drosophila larval salivary glands. In this paper we investigate the localization...
Journal Articles
J Cell Sci (1991) 100 (3): 641–647.
Published: 1 November 1991
... of Biologists 1991 nuclear protein proliferation salivary gland With respect to growth potential in situ as well as in culture, mammalian cells can be classified as proliferating (growing and dividing) or nonproliferating cells. Proliferating cells pass through the cell cycle regularly...