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Keywords: SNX27
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Journal Articles
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Cilia and flagella
J Cell Sci (2022) 135 (10): jcs259396.
Published: 17 May 2022
... the role of retromer in ciliogenesis. VPS35 localized to the primary cilium of mammalian cells, and depletion of VPS26, VPS35, VPS29, SNX1, SNX2, SNX5 or SNX27 led to decreased ciliogenesis. Retromer also coimmunoprecipitated with the centriolar protein, CP110 (also known as CCP110), and was required...
Includes: Supplementary data
Journal Articles
J Cell Sci (2018) 131 (16): jcs218610.
Published: 17 August 2018
... + absorption through inhibition of Na + /H + exchanger 3 (NHE3; also known as SLC9A3). The mechanism(s) by which CT inhibits NHE3 is partially understood, although no drug therapy has been successful at reversing this inhibition. We now describe that CT phosphorylates an amino acid in the PDZ domain of SNX27...
Includes: Supplementary data
Journal Articles
J Cell Sci (2017) 130 (2): 382–395.
Published: 15 January 2017
... of the SNX27–retromer–WASH super complex. Depletion of ANKRD50 in HeLa or U2OS cells phenocopied the loss of endosome-to-cell-surface recycling of multiple transmembrane proteins seen upon suppression of SNX27, retromer or WASH-complex components. Mass-spectrometry-based quantification of the cell surface...
Includes: Supplementary data
Journal Articles