... and Boi2p interact with Sec1p, a protein required for SNARE complex formation and vesicle fusion. Sec1p loses its tip localization in cells depleted of Boi1p and Boi2p but overexpression of Sec1p can partially compensate for their loss. The capacity to simultaneously bind phospholipids, Sec1p, multiple...

... ) 14 2 2006 © The Company of Biologists Limited 2006 2006 Ryanodine receptor Snapin SNARE complex Protein interaction Neurosecretion Ionised calcium (Ca 2+ ) is the trigger for synaptic vesicle fusion with the presynaptic membrane and subsequent neurotransmitter release...

.... In nerve terminals, the V-ATPase membrane domain is present not only in synaptic vesicles but also in the presynaptic plasma membrane, where its density could reach 200 molecules μm –2 . This V-ATPase interacts with VAMP-2 and with the SNARE complexes involved in synaptic vesicle docking and exocytosis...

... Bet1. In vitro formation of this complex on different membranes in yeast lysate was enhanced by the addition of recombinant Sly1. These results indicate that binding of Sly1 to Sed5 enhances trans-SNARE complex formation. Using an in vitro assay, it was shown that a combination of the Q-SNAREs...