... and Boi2p interact with Sec1p, a protein required for SNARE complex formation and vesicle fusion. Sec1p loses its tip localization in cells depleted of Boi1p and Boi2p but overexpression of Sec1p can partially compensate for their loss. The capacity to simultaneously bind phospholipids, Sec1p, multiple...

...-mediated membrane fusion. Nat. Rev. Mol. Cell Biol. 2 , 98 -106. Chheda, M., Ashery, U., Thakur, P., Rettig, J. and Sheng, Z.-H. (2001). Phosphorylation of snapin by PKA modulates its interaction with the SNARE complex. Nat. Cell Biol. 3 , 331 -338. Chou, J.-L., Huang, C.-L., Lai, H.-L...

.... In nerve terminals, the V-ATPase membrane domain is present not only in synaptic vesicles but also in the presynaptic plasma membrane, where its density could reach 200 molecules μm –2 . This V-ATPase interacts with VAMP-2 and with the SNARE complexes involved in synaptic vesicle docking and exocytosis...

... Bet1. In vitro formation of this complex on different membranes in yeast lysate was enhanced by the addition of recombinant Sly1. These results indicate that binding of Sly1 to Sed5 enhances trans-SNARE complex formation. ‡ Author for correspondence (e-mail: [email protected]...