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Keywords: SFPQ
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Journal Articles
J Cell Sci (2021) 134 (4): jcs256602.
Published: 19 February 2021
... RNA foci and bind cellular proteins. This mechanism of action is considered cytotoxic. Translation of the expanded RNA transcripts also leads to the accumulation of toxic dipeptide repeat proteins (DPRs). The RNA-binding protein splicing factor proline and glutamine rich (SFPQ), which is being...
Includes: Supplementary data
Journal Articles
J Cell Sci (2019) 132 (5): jcs224303.
Published: 7 March 2019
... that (G 4 C 2 ) n repeat RNA predominantly associates with essential paraspeckle proteins SFPQ, NONO, RBM14, FUS and hnRNPH and colocalizes with known paraspeckle-associated RNA hLinc-p21. As formation of paraspeckles in motor neurons has been associated with early phases of ALS, we investigated...
Includes: Supplementary data