... it is required for the establishment and maintenance of septate junctions (SJ) (Woods et al., 1996 ; Bilder et al., 2000). Similar to Dlg, its mammalian homologue synapse-associated protein 97 (SAP97/hDlg), associates with the basolateral rather than apical membrane compartment (Wu et al., 1998). Recent...

.... Using the yeast two-hybrid system, we identified the scaffolding protein synapse associated protein 97(SAP97) as a binding partner of the cytoplasmic domain of TACE. By deletions and site-directed mutagenesis, we demonstrated that this interaction involved the PDZ3 domain of SAP97 and the extreme C...

... and heart membrane proteins revealed an interaction between all three Kir2.x C-terminal fusion proteins and the MAGUK protein synapse-associated protein 97 (SAP97). A truncated form of the C-terminal GST-Kir2.2 fusion protein indicated that the last three amino acids (S-E-I) are essential for association...