.... * Author for correspondence (e-mail: thomas@ifn-magdeburg.de ) 1 12 2003 © The Company of Biologists Limited 2004 2004 Epithelial polarity Synapse L27 domain Neuromuscular junction SAP97 Many cell types exhibit an asymmetric subdivison of the plasma membrane...

.... Using the yeast two-hybrid system, we identified the scaffolding protein synapse associated protein 97(SAP97) as a binding partner of the cytoplasmic domain of TACE. By deletions and site-directed mutagenesis, we demonstrated that this interaction involved the PDZ3 domain of SAP97 and the extreme C...

... and heart membrane proteins revealed an interaction between all three Kir2.x C-terminal fusion proteins and the MAGUK protein synapse-associated protein 97 (SAP97). A truncated form of the C-terminal GST-Kir2.2 fusion protein indicated that the last three amino acids (S-E-I) are essential for association...